Results 211 to 220 of about 2,615,185 (246)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Background trade winds and climate sensitivity control the eastern equatorial Pacific warming pattern. [PDF]

Sci Adv
Stuivenvolt-Allen J, Fedorov AV.
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Vertical profile of ambient VOCs in background region of Southwest China from Mt. Fanjing observation. [PDF]

Sci Rep
Yao D, Yang Y, Hu H, Yang J, Li H, Hou X, Zhang H, Zhang X, Liu H, Liu J, Teng Y, Fan Y, Cheng K, Liu J, Yan Y.   +14 more
europepmc   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Multi-decadal high-resolution historical simulations with the ECMWF global atmosphere model. [PDF]

Sci Data
Aengenheyster M, Roberts CD, Aguridan R, Griffith M, Hogan R, Reuter B, Roberts MJ, Sarmany D, Senan R, Stockdale TN, Villaume S, Wachsmann F.   +11 more
europepmc   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Isotopic constraints in methane inversions reveal larger trends in wetland emissions with improved linkage to terrestrial water storage. [PDF]

Nat Commun
Oh Y, Bruhwiler L, Lan X, Halder S, Riddell-Young B, Basu S, Miller JB, Michel S, Schuldt K, Andrews A, Biraud S, Chmura Ł, Lorio TD, Guerette EA, Kozlova E, Liu L, Montaguti S, Morimoto S, Steinbacher M, Umezawa T, Xueref-Remy I, Zazzeri G.   +21 more
europepmc   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Increased maximum carbon release offsets half of the growth trend in annual land carbon sink. [PDF]

Nat Commun
Bai Y, Fu Z, Peñuelas J, Ciais P, Zhang F, Stoy PC, Cescatti A, Sitch S, Migliavacca M, Smith WK, Tang W, Luo Y, Shangguan Y, Wang K, O'Sullivan M.   +14 more
europepmc   +1 more source