Results 31 to 40 of about 797,805 (272)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Electron density diagnostics in atmospheric pressure radio frequency dielectric barrier discharge and discharge with bare electrode [PDF]

open access: yes, 2019
Electron densities in two types of atmospheric pressure radio frequency plasma sources: dielectric barrier discharge (DBD) and discharge with bare electrode (DBE) are investigated by analysis of Stark broadening of Hydrogen Balmer (Hβ) lines.
Cvetanović, Nikola   +6 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Weightlessness simulation system and process [PDF]

open access: yes, 1987
A weightlessness simulator has a chamber and a suit in the chamber. O-rings and valves hermetically seal the chamber. A vacuum pump connected to the chamber establishes a pressure in the chamber less than atmospheric pressure.
Vykukal, Hubert C.
core   +1 more source

On some properties of traveling water waves with vorticity [PDF]

open access: yes, 2008
We prove that for a large class of vorticity functions the crests of any corresponding traveling gravity water wave of finite depth are necessarily points of maximal horizontal velocity. We also show that for waves with nonpositive vorticity the pressure
Varvaruca, Eugen
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Response of the Heavy-Fermion Superconductor CeCoIn$_5$ to Pressure: Roles of Dimensionality and Proximity to a Quantum-Critical Point

open access: yes, 2001
We report measurements of the pressure-dependent superconducting transition temperature $T_c$ and electrical resistivity of the heavy-fermion compound CeCoIn$_5$.
E Lengyel   +29 more
core   +2 more sources

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy