Results 61 to 70 of about 18,724,954 (340)

An Overview of ARTMIP's Tier 2 Reanalysis Intercomparison: Uncertainty in the Detection of Atmospheric Rivers and Their Associated Precipitation

Journal of Geophysical Research: Atmospheres, 2022
Atmospheric rivers, or long but narrow regions of enhanced water vapor transport, are an important component of the hydrologic cycle as they are responsible for much of the poleward transport of water vapor and result in precipitation, sometimes extreme ...
A. Collow, C. Shields, B. Guan, S. Kim, J. M. Lora, E. McClenny, K. Nardi, A. Payne, K. Reid, E. Shearer, R. Tomé, J. Wille, A. M. Ramos, I. Gorodetskaya, L. Leung, T. O’Brien, F. M. Ralph, J. Rutz, P. Ullrich, M. Wehner   +19 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Retraction Note to: Research on coastal atmospheric change and Latin dance performance based on target detection network [PDF]

, 2021
Fan Rao
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Atmospheric new particle formation and growth: review of field observations

Environmental Research Letters, 2018
This review focuses on the observed characteristics of atmospheric new particle formation (NPF) in different environments of the global troposphere. After a short introduction, we will present a theoretical background that discusses the methods used to ...
V. Kerminen, Xuemeng Chen, V. Vakkari, T. Petäjä, M. Kulmala, Federico Bianchi   +5 more
semanticscholar   +1 more source

Examination of the ocean as a source for atmospheric microplastics

PLoS ONE, 2020
Global plastic litter pollution has been increasing alongside demand since plastic products gained commercial popularity in the 1930’s. Current plastic pollutant research has generally assumed that once plastics enter the ocean they are there to stay ...
S. Allen, Deonie Allen, Kerry Moss, G. Le Roux, V. Phoenix, J. Sonke   +5 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Radiance-based retrieval bias mitigation for the MOPITT instrument: the version 8 product [PDF]

Atmospheric Measurement Techniques, 2019
The MOPITT (Measurements of Pollution in the Troposphere) satellite instrument has been making nearly continuous observations of atmospheric carbon monoxide (CO) since 2000.
M. N. Deeter, D. P. Edwards, G. L. Francis, J. C. Gille, D. Mao, S. Martínez-Alonso, H. M. Worden, D. Ziskin, M. O. Andreae, M. O. Andreae   +9 more
doaj   +1 more source