Results 41 to 50 of about 10,000 (260)

Research on Retrieval of Atmospheric Temperature and Humidity Profiles from combined Ground-based Microwave Radiometer and Cloud Radar Observations [PDF]

, 2016
Abstract. This paper focuses on the retrieval of temperature and relative humidity profiles through combining ground-based microwave radiometer observations with those of millimeter-wavelength cloud radar. The cloud-base height and cloud thickness from the cloud radar were added into the atmospheric profile retrieval process, and a back propagation ...
Che, Yunfei, Ma, Shuqing, Xing, Fenghua, Li, Siteng, Dai, Yaru   +4 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A New Algorithm for the Retrieval of Atmospheric Profiles from GNSS Radio Occultation Data in Moist Air and Comparison to 1DVar Retrievals

Remote Sensing, 2019
The Global Navigation Satellite System (GNSS) Radio Occultation (RO) is a key technique for obtaining thermodynamic profiles of temperature, humidity, pressure, and density in the Earth’s troposphere.
Ying Li, Gottfried Kirchengast, Barbara Scherllin-Pirscher, Marc Schwaerz, Johannes K. Nielsen, Shu-peng Ho, Yun-bin Yuan   +6 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Quality Assessment of Operational Fengyun-4B/GIIRS Atmospheric Temperature and Humidity Profile Products

Remote Sensing
As China’s second operational Geostationary Interferometric Infrared Sounder, Fengyun-4B/GIIRS can provide temporally and spatially continuous atmospheric temperature profile (ATP) and atmospheric humidity profile (AHP) information, which can be used in cold wave monitoring and other meteorological applications.
Zhi Zhu, Junxia Gu, Fang Yuan, Chunxiang Shi   +3 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Drone-Based Vertical Atmospheric Temperature Profiling in Urban Environments

Drones, 2023
The accurate and detailed measurement of the vertical temperature, humidity, pressure, and wind profiles of the atmosphere is pivotal for high-resolution numerical weather prediction, the determination of atmospheric stability, as well as investigation ...
Jokūbas Laukys, Bernardas Maršalka, Ignas Daugėla, Gintautas Stankūnavičius   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Measurement of Solar Absolute Brightness Temperature Using a Ground-Based Multichannel Microwave Radiometer

Remote Sensing, 2021
Ground-based multichannel microwave radiometers (GMRs) can observe the atmospheric microwave radiation brightness temperature at K-bands and V-bands and provide atmospheric temperature and humidity profiles with a relatively high temporal resolution ...
Lianfa Lei, Zhenhui Wang, Yingying Ma, Lei Zhu, Jiang Qin, Rui Chen, Jianping Lu   +6 more
doaj   +1 more source