Results 71 to 80 of about 14,328 (280)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

The Energy–Quality Nexus in Atmospheric Water Generation: A Review of Contaminants, Performance Metrics, and the Proposal of the AWEQI

Toxics
Atmospheric water (AW) is currently recognized as a promising solution to mitigate the global water crisis. Nevertheless, its harvesting techniques should balance three main aspects: energy consumption, yield, and the quality of produced water.
Lucia Cattani, Paolo Cattani, Anna Magrini   +2 more
doaj   +1 more source

A Semi-Interpenetrating Network Sorbent of Superior Efficiency for Atmospheric Water Harvesting and Solar-Regenerated Release. [PDF]

ACS Appl Mater Interfaces
Water is readily available nearly anywhere as vapor. Thus, atmospheric water harvesting (AWH) technologies are seen as a promising solution to support sustainable water production. This work reports a novel semi-interpenetrating network, which integrates
Elwadood SNA, Farinha ASF, Al Wahedi Y, Al Alili A, Witkamp GJ, Dumée LF, Karanikolos GN.   +6 more
europepmc   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Enhanced Atmospheric Water Harvesting in Metal-Organic Frameworks [PDF]

, 2023
The dawn of the 21st century has ushered in a water crisis, intensified by the dual challenges of climate change and burgeoning population growth. Freshwater reservoirs are being strained, and while there are existing water generation technologies, they ...
Zheng, Zhiling
core  

Superlubricity and Corrosion Inhibition Properties of Solvate Ionic Liquids in Hybrid Carbon Fiber Reinforced Plastic–Steel Interfaces

Advanced Engineering Materials, EarlyView.
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees, Timothy Harte, Bhagya Dharmasiri, Y. Athulya Wickramasingha, David J. Hayne, Daniel J. Eyckens, Luke C. Henderson   +6 more
wiley   +1 more source

Advances in Atmospheric Water Harvesting Hydrogels: A Review of Material Design, System Integration, and Practical Applications

Small Structures
The global freshwater shortage poses severe threats to human life, thus driving extensive research on sorbent‐based atmospheric water harvesting (SAWH). Hydrogel materials, owing to their unique 3D network structures, possess exceptional capabilities in ...
Ting‐Ting Li, Pengle Cao, Wangkai Jiang, Ke‐Qin Zhang   +3 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Thermodynamics of hydrogels for applications in atmospheric water harvesting, evaporation, and desalination

Physical Chemistry Chemical Physics, 2022
A reformulation of hydrogel thermodynamics, focusing on water in hydrogel for atmospheric water harvesting, solar interfacial evaporation, and desalination is presented.
openaire   +4 more sources