Results 121 to 130 of about 696,040 (268)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Elektron spin rezonans (ESR) ve termolüminesans (TL) teknikleri ile gıdaların gama ışınları ile ışınlanıp ışınlanmadıklarının tespit edilmesi

, 2011
TENMAK D.N.. 9970Bu çalışmada selüloz, kemik ve şeker içeren çeşitli gıda örneklerinin Elektron Spin rezonans (ESR) tekniği ile teşhisi yapılmıştır.
Aydın, Talat, Demirtaş, Hayrunnisa, Yüce, Ülkü Rabia, Aydaş, Canan, Engin, Birol, Zeyrek, C. Tuğrul, Tepe Çam, Semra   +6 more
core  

Minecraft’s Atom

Press Start
Given that the fundamental element of Minecraft (Mojang Studios, 2011) is appreciably large, what its players discover is a sandbox-style game in which the ubiquitous block, Minecraft’s atom, stands for an unparalleled degree of immediacy. Alongside the
Erick Verran
doaj  

BONAFIDE: a Python framework for the calculation of local features for atoms and bonds in molecules. [PDF]

J Cheminform
Sigmund LM, Assante M, Ball M, Kabeshov M.   +3 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Structural and dynamical consistency in lipid vesicles across all-atom, MARTINI, and dissipative particle dynamics. [PDF]

RSC Adv
Xu W, Wei X, Chong G, Dahal U, Cui Q, Hernandez R.   +5 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Atom, ion, dan molekul beserta aplikasinya.

, 2017
Buku ini menampilkan konsep yang lebih lengkap mengenai atom, ion, dan molekul sehingga siswa diharapkan lebih mudah mencari informasi mengenai materi tersebut.iv, 60 hlm.: ilus.; 21 ...
Suntari, Anis Dyah Rufaida, Zain Mustaghir   +2 more
core