Results 21 to 30 of about 696,040 (268)

Superfluid flow above the critical velocity

open access: yesScientific Reports, 2017
Superfluidity and superconductivity have been widely studied since the last century in many different contexts ranging from nuclear matter to atomic quantum gases.
A. Paris-Mandoki   +5 more
doaj   +1 more source

Reduction of background scattered light in vacuum systems for cold atoms experiments

open access: yesAIP Advances, 2020
Recent advances in the understanding and control of cold atom systems have resulted in devices with extraordinary metrological performance. To further improve the performance in these systems, additional methods of noise reduction are needed.
J. Vovrosh   +8 more
doaj   +1 more source

Lipid nanoparticles with aptamers enable targeted mRNA delivery to CD4⁺ T cells

open access: yesDrug Delivery
In vivo genetic engineering of T cells could overcome the logistical, biological, and safety challenges of ex vivo modification, but effective and safe delivery systems remain limited by a lack of cellular specificity.
Shrey Shah   +9 more
doaj   +1 more source

Development of Plastic Scintillation Fiber Array Detector Based on SiPM

open access: yesHe huaxue yu fangshe huaxue
The decommissioning management process of nuclear facilities requires rapid classification and detection of soil radionuclides and contamination levels, of which 90Sr is one of the focus nuclides.
Peng MA   +4 more
doaj   +1 more source

Atom-hybridization for synthesis of polymetallic clusters

open access: yesNature Communications, 2018
Multimetallic clusters are difficult to synthesize with control over elemental composition and organization. Here, the authors use dendrimers to precisely template the formation of five-element sub-nanoclusters, providing an elegant route to otherwise ...
Takamasa Tsukamoto   +4 more
doaj   +1 more source

Usage of Natural Uranium in Nuclear Reactors

open access: yesГлобальная ядерная безопасность, 2022
The paper reviews the modern tendencies in the development of the world nuclear energy sector and progress in research of renewable energy technologies. Due to the unique advantages of the nuclear energy generation it proves to be very prospective source
A. V. Goncharuk
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics, and pharmacodynamics of ABP-671 in healthy participants and patients with hyperuricemia and gout: a proof-of-concept study

open access: yesArthritis Research & Therapy
Background This proof-of-concept study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ABP-671, a novel URAT1 inhibitor, in healthy participants and in patients with hyperuricemia and gout.
Jin Wang   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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