Results 191 to 200 of about 65,224 (262)

Pathfinder experiments with atom interferometry in the Cold Atom Lab onboard the International Space Station. [PDF]

Nat Commun
Williams JR, Sackett CA, Ahlers H, Aveline DC, Boegel P, Botsi S, Charron E, Elliott ER, Gaaloul N, Giese E, Herr W, Kellogg JR, Kohel JM, Lay NE, Meister M, Müller G, Müller H, Oudrhiri K, Phillips L, Pichery A, Rasel EM, Roura A, Sbroscia M, Schleich WP, Schneider C, Schubert C, Sen B, Thompson RJ, Bigelow NP.   +28 more
europepmc   +1 more source

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
Triblock copolymer‐reinforced liposomal mimics of extracellular vesicles are engineered with tunable membrane elasticity. A semi‐elastic formulation (Tri‐ARTEX8:2) co‐encapsulating stem cell cytosolic extract and AntagomiR155 targets inflamed joints via the ELVIS effect, reprograms macrophages from M1 to M2, and markedly alleviates collagen‐induced ...
Dahwun Kim, Hwira Baek, Su Yeon Lim, Min Sang Lee, Siyan Lyu, Jihyun Lee, Tun Naw Sut, Marta Gonçalves, Jeong Yi Kang, Joshua A. Jackman, Jin Woong Kim, Ji Hoon Jeong   +11 more
wiley   +1 more source

Exploring Surface-Enhanced Raman Spectroscopy of Pyrazine-2-Carbonitrile for Indirect Label-Free Albumin Quantification in an <i>In Vitro</i> Endothelium Permeability Assay. [PDF]

Anal Chem
Klement WJN, Duijnstee DR, Telle V, Staykov A, Browne WR, Verpoorte E.   +5 more
europepmc   +1 more source

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

Advanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim, Inhyuk Hwang, Juhee Seo, Chaiwon Kim, In‐Jeong Choi, Miran Kang, Min‐Seok Rha, Youngjae Hong, Jooyoung Kim, Seung‐Ki Baek, Jung‐Hwan Park, Hyung‐Ju Cho, Kihyuck Kwak   +12 more
wiley   +1 more source

Chemical Composition and Backbone Modifications Define Deformability of Nucleic Acid Nanoparticles. [PDF]

ACS Nano
Pandey L, Panigaj M, Radwan Y, Chhabra H, Chen Y, Aksimentiev A, Afonin KA, Wanunu M.   +7 more
europepmc   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Towards a Better Understanding of the Human Health Risk of Per- and Polyfluoroalkyl Substances Using Organoid Models. [PDF]

Bioengineering (Basel)
Xu H, Kang J, Gao X, Lan Y, Li M.
europepmc   +1 more source

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

Advanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra, Kai Yu, Jason Rogalski, Taylor Olivia Da Silva, Parisa Golesorkhi, Madeleine Goldstein, Dana V. Devine, Jayachandran N. Kizhakkedathu   +7 more
wiley   +1 more source

Decoding phospho-regulation and flanking regions in autophagy-associated short linear motifs. [PDF]

Commun Biol
Utichi M, Antonescu ON, Sora V, Marjault HB, Tiberti M, Maiani E, Lambrughi M, Papaleo E.   +7 more
europepmc   +1 more source