Results 171 to 180 of about 23,949,715 (384)

Disentangling Coexisting Structural Order Through Phase Lock-In Analysis of Atomic-Resolution STEM Data

open access: green, 2022
Berit H. Goodge   +6 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Atomic data and electron-impact broadening effect in DO white dwarf atmospheres: Si vi [PDF]

open access: green, 2008
Rafik Hamdi   +5 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Measurement of production cross-sections of natTi(p,x)43K,43,44m,44g,46g,47,48Sc,48V reactions up to 50 MeV

open access: yesNuclear Engineering and Technology
The cross-sections of natTi(p,x) reactions were measured up to 50 MeV by using off-line γ-ray spectrometry and stacked-foil activation technique. The activation experiment was conducted using 57 MeV proton beams from the proton accelerator at the Korea ...
Dal-Ho Moon   +3 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cluster-mining: an approach for determining core structures of metallic nanoparticles from atomic pair distribution function (PDF) data [PDF]

open access: bronze, 2019
Soham Banerjee   +8 more
openalex   +1 more source

Home - About - Disclaimer - Privacy