Results 181 to 190 of about 23,949,715 (384)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Atomic data: James Mackenzie Lecture 2015. [PDF]

Br J Gen Pract, 2016
Sullivan F.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Prospect for measurement of the CP-violating phase  $$\phi _s$$ ϕ s in the $$B_{s}\rightarrow J/\psi \phi $$ B s → J / ψ ϕ channel at a future Z factory

European Physical Journal C: Particles and Fields
The CP-violating phase $$\phi _s$$ ϕ s , the $$B_{s}$$ B s decay width ( $$\varGamma _s$$ Γ s ), and the $$B_{s}$$ B s decay width difference ( $$\varDelta \varGamma _s$$ Δ Γ s ) are sensitive probes to new physics and can constrain the heavy quark ...
Xiaomei Li, Manqi Ruan, Mingrui Zhao
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A dataset of high-efficiency atomic orbital data for first-principles calculations of large atomic systems [PDF]

Wenmei Zhang, Peize Lin, Mohan Chen, Lixin HE   +3 more
openalex   +1 more source

Availability of deposited atomic coordinates from the Cambridge Crystallographic Data Centre [PDF]

, 1985

openalex   +1 more source

ATOMIC Simulations and Experimental Data for CaCO3 Mixtures

, 2021
J. Colgan, Elizabeth J. Judge, K. Sham Bhat, Kary Myers, Earl Lawrence   +4 more
openalex   +2 more sources

Robustness test of the spacegroupMining model for determining space groups from atomic pair distribution function data [PDF]

, 2022
Lei Lan, Chia‐Hao Liu, Qiang Du, Simon J. L. Billinge   +3 more
openalex   +1 more source