Results 101 to 110 of about 8,492,929 (374)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The First Cold Antihydrogen

, 2004
Antihydrogen, the atomic bound state of an antiproton and a positron, was produced at low energy for the first time by the ATHENA experiment, marking an important first step for precision studies of atomic antimatter.
A. Bouchta, A. Fontana, A. Rotondi, A. Variola, Amoretti, Amoretti, Amoretti, Amoretti, Baur, Blanford, C. Amsler, C. Carraro, C. Regenfus, C.L. Cesar, Cesar, Charlton, D. Lindelöf, D.P.van der Werf, Dubin, E.Lodi Rizzini, Estrada, Fujiwara, Fujiwara, Fujiwara, G. Bonomi, G. Testera, Gabrielse, Gabrielse, H. Pruys, J.S. Hangst, Jørgensen, Kuno, L.V. Jørgensen, M. Amoretti, M. Charlton, M. Doser, M. Macri, M. Marchesotti, M.C. Fujiwara, Morenzoni, N. Madsen, Nagamine, Niering, P. Genova, P. Montagna, P. Riedler, P.D. Bowe, R. Funakoshi, R. Landua, R.S. Hayano, Regenfus, Surko, V. Filippini, V. Lagomarsino, Y. Yamazaki   +54 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Coulomb effects in high-energy $e^+e^-$ electroproduction by a heavy charged particles in an atomic field

, 2017
The cross section of high-energy $e^+e^-$ pair production by a heavy charged particle in the atomic field is investigated in detail. We take into account the interaction with the atomic field of $e^+e^-$ pair and a heavy particle as well. The calculation
Krachkov, P. A., Milstein, A. I.
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Low energy monopole Modes of a Trapped atomic Fermi Gas

, 2002
We consider the low energy collective monopole modes of a trapped weakly interacting atomic Fermi gas in the collisionless regime. The spectrum is calculated for varying coupling strength and chemical potential.
G. M. Bruun, H. T. C. Stoof, J. P. Blaizot, L. P. Gorkov   +3 more
core   +1 more source

Recent progress in the application of in situ atomic force microscopy for metal anode processes in energy storage batteries

, 2023
J.Y. Wang, Ruizhi Liu, Zhen-Zhen Shen, Jianxin Tian, Rui Wen   +4 more
openalex   +1 more source

New development of atomic layer deposition: processes, methods and applications

Science and Technology of Advanced Materials, 2019
Atomic layer deposition (ALD) is an ultra-thin film deposition technique that has found many applications owing to its distinct abilities. They include uniform deposition of conformal films with controllable thickness, even on complex three-dimensional ...
P. Oviroh, R. Akbarzadeh, D. Pan, R. Coetzee, T. Jen   +4 more
semanticscholar   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

From quantum alchemy to Hammett's equation: Covalent bonding from atomic energy partitioning [PDF]

, 2022
Michael J. Sahre, Guido Falk von Rudorff, O. Anatole von Lilienfeld   +2 more
openalex   +1 more source