Results 31 to 40 of about 6,328,901 (300)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Sub-barrier Fusion and Neutron Transfer with Positive Q-value

EPJ Web of Conferences, 2014
Fusion excitation functions of 16O+76Ge and 18O+74Ge have been measured with high precision at energies near and below the Coulomb barrier. Coupled-channels calculations including inelastic excitations well reproduce the experimental fusion excitation ...
Lin C. J., Jia H. M., Zhang H. Q., Xu X. X., Yang F., Yang L., Bao P. F., Sun L. J., Liu Z. H.   +8 more
doaj   +1 more source

Application of a first-order method to estimate the failure probability of component subjected to thermal transients for optimization of design parameters

Mechanical Engineering Journal, 2023
The Japan Atomic Energy Agency has been developing “Advanced Reactor Knowledge- and AI-aided Design Integration Approach through the whole plant lifecycle (ARKADIA)” to offer the best solutions for challenges in the design and operation of nuclear plants.
Satoshi OKAJIMA, Takero MORI, Norihiro KIKUCHI, Masaaki TANAKA, Masashi MIYAZAKI   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Neutronics/thermal-hydraulics coupling simulation using JAMPAN in a single BWR assembly

Mechanical Engineering Journal
We have aimed to realize high-fidelity neutronics/thermal-hydraulics coupling simulation to provide simulation results that can be used as validation data for reactor analysis codes.
Tomohiro KAMIYA, Taku NAGATAKE, Ayako ONO, Kenichi TADA, Ryoichi KONDO, Yasunobu NAGAYA, Hiroyuki YOSHIDA   +6 more
doaj   +1 more source

Experimental study on scabbing limit of local damage to reinforced concrete panels subjected to oblique impact by projectile with semispherical nose

Mechanical Engineering Journal, 2023
The influence evaluation against projectile impacts has attracted much attention for the safety assessment of nuclear-facility buildings subjected to projectiles, such as tornado missiles or aircraft.
Yukihiko OKUDA, Zuoyi KANG, Akemi NISHIDA, Haruji TSUBOTA, Yinsheng LI   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Atomic Energy Commission Reports [PDF]

, 1962
From introduction: "This is the fourth of a series of quarterly reports which will cover the progress and results from the conceptual design, economic evaluations and research and development work performed by the General Electric Company as part of the ...
U.S. Atomic Energy Commission
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Optimization in granulation conditions for adsorbent of extraction chromatography

Mechanical Engineering Journal
Japan Atomic Energy Agency has been working on development of extraction chromatography technology for recovery of trivalent minor actinides (MA(III): Am, Cm) from high-level radioactive waste generated in reprocessing of spent fuel.
Kenta HASEGAWA, Ichiro GOTO, Yasunori MIYAZAKI, Hiromu AMBAI, Sou WATANABE, Masayuki WATANABE, Yuichi SANO, Masayuki TAKEUCHI   +7 more
doaj   +1 more source