Results 61 to 70 of about 1,330,445 (333)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Calibration Technology of Ionization Chamber Tritium Monitor

He huaxue yu fangshe huaxue, 2023
The ionization chamber tritium monitor is the most important online monitoring equipment for monitoring the concentration of tritium in the air. In order to solve the problem of quantity value transmission, the calibration technology of ionization ...
LI Ming, XU Li-jun, MAO Na-qing, YE Hong-sheng, LUO Rui, LIN Min   +5 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Study on Influence Factors of Calcined Products From Simulated HLLW Based on Gaussian Kriging Agent Model

He huaxue yu fangshe huaxue, 2023
The calcined product of the high-level liquid waste(HLLW) is the intermediate product of two-step cold crucible glass solidification process. Its performance(such as water content, bulk density, denitration efficiency and so on) has an important impact ...
ZHANG Hua, LI Bao-jun, LI Yang, ZHANG Ke-qian, HE Cheng, HONG Ye   +5 more
doaj   +1 more source

Coupled electron and phonon transport in one-dimensional atomic junctions

, 2007
Employing the nonequilibrium Green's function method, we develop a fully quantum mechanical model to study the coupled electron-phonon transport in one-dimensional atomic junctions in the presence of a weak electron-phonon interaction. This model enables
H. Haug, J. T. Lü, Jian-Sheng Wang, L. Kadanoff, L. V. Keldysh, S. Datta   +5 more
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Analytical study of perforation damage in reinforced concrete slabs subjected to oblique impact by projectiles with different nose shapes

Mechanical Engineering Journal, 2020
Considerable research has been carried out to establish a rational assessment method for nuclear power plants against external projectile impact. Most of the empirical formulas have been proposed to quantitatively investigate local damage to reinforced ...
Zuoyi KANG, Yukihiko OKUDA, Akemi NISHIDA, Haruji TSUBOTA, Yinsheng LI   +4 more
doaj   +1 more source

Exact solution, scaling behaviour and quantum dynamics of a model of an atom-molecule Bose-Einstein condensate

, 2002
We study the exact solution for a two-mode model describing coherent coupling between atomic and molecular Bose-Einstein condensates (BEC), in the context of the Bethe ansatz.
Drummond P. D., Hope J. J., HUAN-QIANG ZHOU, Javanainen J., JON LINKS, Koštrun M., Kuznetsov V. B., ROSS H. McKENZIE, Rybin A., Vardi A., Wiegmann P. B.   +10 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Design of the offline test electronics for the nozzle system of proton therapy

Scientific Reports
A set of nozzle equipment for proton therapy is currently under development at China Institute of Atomic Energy (CIAE). To facilitate the off-line commissioning of the whole equipment, a set of ionization chamber signal generation system, known as the ...
Peng Huang, Zhiguo Yin, Tianjian Bian, Shigang Hou, Fengping Guan, Shizhong An, Yang Wang, Tianjue Zhang, Luyu Ji, Lipeng Wen, Xueer Mu   +10 more
doaj   +1 more source