Results 71 to 80 of about 7,213,834 (363)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Study for s-process using neutron beam provided from ANNRI of J-PARC

EPJ Web of Conferences, 2016
Most isotopes heavier than iron are synthesized by the slow neutron capture reaction process (s-process) in stars. Isomers in stable isotopes have sometimes an important role as a branching point in nucleosynthesis flow in the s-process. An isomer with a
Hayakawa Takehioto, Toh Yosuke, Kimura Akira, Nakamura Shoji, Shizuma Toshiyuki, Harada Hideo   +5 more
doaj   +1 more source

Impact simulations on local damage of reinforced concrete panel influenced by projectile nose shape

Mechanical Engineering Journal, 2020
Most impact research has been presented on the basis of impact tests and numerical analysis performed by rigid projectile impact perpendicular to the target structure. On the other hand, there are only few reports on impacts at an oblique angle.
Zuoyi KANG, Akemi NISHIDA, Yukihiko OKUDA, Haruji TSUBOTA, Yinsheng LI   +4 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Development and validation of a GF-AAS method and its application for the trace level determination of Pb, Cd, and Cr in fish feed samples commonly used in the hatcheries of Bangladesh

Journal of Analytical Science and Technology, 2017
Background A sensitive, accurate and precise method was developed and validated in regard to Council Directive 333/2007/EC, Commission Decision 657/2002/EC, ISO/IEC 17025:2005 and EURACHEM 1998 for the trace level determination of Lead (Pb), Cadmium (Cd)
A. K. M. Atique Ullah, M. A. Maksud, S. R. Khan, L. N. Lutfa, Shamshad B. Quraishi   +4 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Stress, strain, neutron transport and radiation effects in a full fusion tokamak device: A virtual MAST-U study [PDF]

EPJ Web of Conferences
A finite-element method (FEM) model for the Mega-Ampere Spherical Tokamak - Upgrade (MAST-U) fusion tokamak has been developed to evaluate stress and deformations in the full device structure and to assess the stability of the whole tokamak with respect ...
Reali Luca, Ellis William M.E., Gray Ander, Boleininger Max, Davis Andrew, Brooks Helen M., Katramados Ioannis, Thornton Andrew J., Buchanan James, Dudarev Sergei L.   +9 more
doaj   +1 more source

CHIANTI—An Atomic Database for Emission Lines. XV. Version 9, Improvements for the X-Ray Satellite Lines [PDF]

Astrophysical Journal Supplement Series, 2019
CHIANTI contains a large quantity of atomic data for the analysis of astrophysical spectra. Programs are available in IDL and Python to perform calculation of the expected emergent spectrum from these sources.
K. Dere, G. Zanna, P. Young, E. Landi, R. Sutherland   +4 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source