Results 81 to 90 of about 7,380,852 (360)

Study for s-process using neutron beam provided from ANNRI of J-PARC

open access: yesEPJ Web of Conferences, 2016
Most isotopes heavier than iron are synthesized by the slow neutron capture reaction process (s-process) in stars. Isomers in stable isotopes have sometimes an important role as a branching point in nucleosynthesis flow in the s-process. An isomer with a
Hayakawa Takehioto   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Development and validation of a GF-AAS method and its application for the trace level determination of Pb, Cd, and Cr in fish feed samples commonly used in the hatcheries of Bangladesh

open access: yesJournal of Analytical Science and Technology, 2017
Background A sensitive, accurate and precise method was developed and validated in regard to Council Directive 333/2007/EC, Commission Decision 657/2002/EC, ISO/IEC 17025:2005 and EURACHEM 1998 for the trace level determination of Lead (Pb), Cadmium (Cd)
A. K. M. Atique Ullah   +4 more
doaj   +1 more source

Impact simulations on local damage of reinforced concrete panel influenced by projectile nose shape

open access: yesMechanical Engineering Journal, 2020
Most impact research has been presented on the basis of impact tests and numerical analysis performed by rigid projectile impact perpendicular to the target structure. On the other hand, there are only few reports on impacts at an oblique angle.
Zuoyi KANG   +4 more
doaj   +1 more source

Peaceful Uses of Atomic Energy [PDF]

open access: yesNature, 1956
Proceedings of the International Conference on the Peaceful Uses of Atomic Energy Held in Geneva, 8 August–20 August, 1955. Vol. 8: Production Technology of the Materials Used for Nuclear Energy. Pp. ix + 627. Vol. 9: Reactor Technology and Chemical Processing. Pp. x + 771. (New York: United Nations; London: H.M.
openaire   +4 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

New development of atomic layer deposition: processes, methods and applications

open access: yesScience and Technology of Advanced Materials, 2019
Atomic layer deposition (ALD) is an ultra-thin film deposition technique that has found many applications owing to its distinct abilities. They include uniform deposition of conformal films with controllable thickness, even on complex three-dimensional ...
P. Oviroh   +4 more
semanticscholar   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

open access: yesFEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki   +3 more
wiley   +1 more source

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