Results 191 to 200 of about 29,939 (265)

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Conventional Chromatographic Techniques and Biosensors for Mercury Speciation in Seafood: A Systematic Review. [PDF]

Foods
Abouelenein D, Henares M, Fuentes A, Fernández-Segovia I, M Barat J, Loeschner K, Duedahl-Olesen L, Gómez-Gómez M, Griol A, J Sloth J.   +9 more
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Structural basis for the dynamic conformations of AP-4 and its association with ARF1. [PDF]

Nat Commun
Wang Y, Li W, Qiu Y, Wu S, Hong L, Zhao Y, Feng W.   +6 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Synthesis, spectroscopic, characterization, antimicrobial, DNA interaction, DFT and molecular docking studies of a new Cu(II)-Schiff base complex. [PDF]

Sci Rep
Mahmoud EG, Ismail EH, Abdel Aziz AA, Abdel-Latif SA, Mobarez SN.   +4 more
europepmc   +1 more source

Ag-Doped ZnO Quantum Dots for Fluorescence-Based Detection of Trace Cr(VI) from River Water and Fish samples. [PDF]

J Fluoresc
Shifera GA, Kitte SA, Beyene TT, Gure A.
europepmc   +1 more source

Biomolecule Detection Methods Based on Nanoparticle Approaches. [PDF]

ACS Omega
Li T, Datson Z, Darwish N, Lopez-Ruiz FJ.   +3 more
europepmc   +1 more source

Synthesis and In Situ Application of a New Fluorescent Probe for Visual Detection of Copper(II) in Plant Roots. [PDF]

Molecules
Hu D, Guan J, Chen W, Zhang L, Fan X, Zhou G, Bao Z.   +6 more
europepmc   +1 more source

A Highly Sensitive Water-Soluble Donor-Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics. [PDF]

J Phys Chem B
Scattolini G, Torres-Méndez CE, Valli D, Kuska MI, Kaul N, Hammarström L, Tian H, Maj M.   +7 more
europepmc   +1 more source