Results 41 to 50 of about 96,662 (347)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Erbium dopants in silicon nanophotonic waveguides [PDF]

, 2020
The combination of established nanofabrication with attractive material properties makes silicon a promising material for quantum technologies, where implanted dopants serve as qubits with high density and excellent coherence even at elevated ...
Gritsch, Andreas, Merkel, Benjamin, Reiserer, Andreas, Weiss, Lorenz   +3 more
core   +3 more sources

An accurate determination of the Avogadro constant by counting the atoms in a 28Si crystal

, 2010
The Avogadro constant links the atomic and the macroscopic properties of matter. Since the molar Planck constant is well known via the measurement of the Rydberg constant, it is also closely related to the Planck constant.
Andreas, B., Azuma, Y., Bartl, G., Becker, P., Bettin, H., Borys, M., Busch, I., Fuchs, P., Fujii, K., Fujimoto, H., Gray, M., Kessler, E., Krumrey, M., Kuetgens, U., Kuramoto, N., Mana, G., Manson, P., Massa, E., Mizushima, S., Nicolaus, A., Picard, A., Pramann, A., Rienitz, O., Schiel, D., Valkiers, S., Waseda, A.   +25 more
core   +1 more source

Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5. [PDF]

, 2017
The phosphorylation of agonist-occupied G-protein-coupled receptors (GPCRs) by GPCR kinases (GRKs) functions to turn off G-protein signaling and turn on arrestin-mediated signaling.
Adams, Christopher M., Benovic, Jeffrey L., Betz, Robin M., Chung, Ka Young, Dror, Ron O., Du, Yang, Duc, Nguyen Minh, Kobilka, Brian K., Komolov, Konstantin E., Leib, Ryan D., Patra, Dhabaleswar, Rodrigues, João P.G.L.M., Skiniotis, Georgios   +12 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cold heteronuclear atom-ion collisions

, 2010
We study cold heteronuclear atom ion collisions by immersing a trapped single ion into an ultracold atomic cloud. Using ultracold atoms as reaction targets, our measurement is sensitive to elastic collisions with extremely small energy transfer.
Carlo Sias, Christoph Zipkes, Lothar Ratschbacher, Michael Köhl, P. Langevin, Stefan Palzer   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Application and Development of Electrochemical Hydride Generation in Atomic Spectrometry Analysis

Yankuang ceshi, 2014
Electrochemical hydride generation (EcHG) is an effective gas sampling method developed for atomic spectrometers. Electrode reactions are adopted in an electrochemical cell to generate hydride and mercury vapor in the cathode chamber for EcHG instead of ...
ZU Wen-chuan, WANG Yu, WU Yan-wen, CHEN Shun-cong   +3 more
doaj   +2 more sources

A literature review of analytical techniques for materials characterisation of painted textiles - Part 2: spectroscopic and chromatographic analytical instrumentation [PDF]

, 2017
Part Two of this Literature Review of analytical techniques for materials characterisation of painted textiles focusses on the application of vibrational and x-ray spectroscopic and chromatographic techniques used in the analysis of painted textiles to ...
Lennard, Frances, Smith, Margaret, Thompson, Karen   +2 more
core   +1 more source