Results 41 to 50 of about 90,914 (346)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Coupled techniques for arsenic speciation in food and drinking water: A review [PDF]

, 2015
Arsenic is ubiquitous in nature appearing in various chemical forms. The toxicity, environmental mobility and accumulation of As in living organisms depends on the form in which the element exists, thus requiring techniques which can identify specific ...
Foulkes, ME, Hill, SJ, Sadee, B
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Intensity of atomic fluorescence as a function of atomic concentration in atomic fluorescence flame spectrometry

Spectrochimica Acta Part B: Atomic Spectroscopy, 1967
Abstract Expressions for the intensity of atomic fluorescence of atoms in atomic fluorescence flame spectrometry are derived by a simple approach. In this approach the atomic fluorescence of atoms at low and high concentrations excited by narrow line and continuous sources is considered, and the approach is general for resonance, stepwise-line, and ...
Department of Chemistry, University of Florida, Gainesville, Florida, USA ( host institution ), Winefordner, J.D., Parsons, M.L., Mansfield, J.M., McCarthy, W.J.   +4 more
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The Application and Development of Electrochemical Hydride Generation in Atomic Spectrometry Analysis

Yankuang ceshi, 2014
Electrochemical hydride generation (EcHG) is an effective gas sampling method developed for atomic spectrometers. Electrode reactions are adopted in an electrochemical cell to generate hydride and mercury vapor in the cathode chamber for EcHG instead of ...
ZU Wen-chuan, WANG Yu, WU Yan-wen, CHEN Shun-cong   +3 more
doaj   +2 more sources

Geochemical Characteristics of Selenium in Surface Soil of Central Townships in Zhaojue County, Sichuan Province

Yankuang ceshi, 2022
BACKGROUND Selenium (Se) is one of the essential trace elements for humans, and an important way for humans to obtain and supplement selenium is by eating natural selenium-enriched agricultural products. The geochemical characteristics of selenium in the
ZHAO Chen, SUN Binbin, HE Ling, WU Chao, CHENG Xiaomeng, ZENG Daoming, LIU Dong   +6 more
doaj   +1 more source

Tracing Noble Gas Radionuclides in the Environment [PDF]

, 2004
Trace analysis of radionuclides is an essential and versatile tool in modern science and technology. Due to their ideal geophysical and geochemical properties, long-lived noble gas radionuclides, in particular, 39Ar (t1/2 = 269 yr), 81Kr (t1/2 = 2.3x10^5
Broecker WS, Collon P, Craig H, Fairbank WM, Finkel RC, Firestone RB, Graedel TE, Hurst GS, Letokhov VS, Office of Technology Assessment (OTA), Paul M, Philippe Collon, Proc. Consultant Meet., Rodriguez J, Thonnard N, Walter Kutschera, Young L, Zheng-Tian Lu   +17 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Adsorption Kinetics of Low Mercury Solution with Durian Shell and Activated Carbon

Yankuang ceshi, 2022
BACKGROUND The direct discharge of Hg(Ⅱ) is harmful to the environment. At present, activated carbon is used to remove it, but the production of activated carbon through high-temperature pyrolysis and activation is very expensive.
ZHAO Zi-ke, CHEN Chun-liang, KE Sheng, ZHAO Li-rong, ZHANG Ji-biao, LI Jian   +5 more
doaj   +1 more source