Results 51 to 60 of about 96,662 (347)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Adsorption Kinetics of Low Mercury Solution with Durian Shell and Activated Carbon

Yankuang ceshi, 2022
BACKGROUND The direct discharge of Hg(Ⅱ) is harmful to the environment. At present, activated carbon is used to remove it, but the production of activated carbon through high-temperature pyrolysis and activation is very expensive.
ZHAO Zi-ke, CHEN Chun-liang, KE Sheng, ZHAO Li-rong, ZHANG Ji-biao, LI Jian   +5 more
doaj   +1 more source

Observation of single collisionally cooled trapped ions in a buffer gas [PDF]

, 2007
Individual Ba ions are trapped in a gas-filled linear ion trap and observed with a high signal-to-noise ratio by resonance fluorescence. Single-ion storage times of ~5 min (~1 min) are achieved using He (Ar) as a buffer gas at pressures in the range 8e-5
A. Odian, A. Piepke, A. Pocar, B. Flatt, B. Mong, C. Hall, C. Hargrove, C. Virtue, C. Y. Prescott, D. Hallman, D. Mackay, D. S. Leonard, D. Schenker, D. Sinclair, E. Badareu, E. Baussan, F. LePort, G. Gratta, G. Janik, H. Dehmelt, J. Farine, J. Hodgson, J. Wodin, J.-L. Vuilleumier, J.-M. Vuilleumier, K. Hall, K. O’Sullivan, K. Skarpaas, K. Wamba, M. Breidenbach, M. Danilov, M. Green, M. Moe, M. Montero Díez, M. Nielsen, P. C. Rowson, P. Fierlinger, P. Weber, R. Conley, R. DeVoe, R. March, R. Neilson, S. Waldman, V. Strickland, W. Fairbank, W. Paul, Y. Martin, Y. Moriwaki   +47 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Determination of Antimony in Gold-Antimony Ore and Antimony Ore by Inductively Coupled Plasma-Atomic Emission Spectrometry with Four Acids Dissolution

Yankuang ceshi, 2013
There are reliable chemical analysis methods for determining high, low and trace amounts of antimony in gold-antimony ore and antimony ore. However, the volumetric method for low content antimony measurements has a low analysis efficiency and involves a ...
WEI Yi, DOU Xiang-li, JU Li-pei, ZHANG Wang-qiang, ZHAO Wei-hua, YU Zhi-feng, MAO Zheng-cai   +6 more
doaj  

Metabolic response of human osteoarthritic cartilage to biochemically characterized collagen hydrolysates [PDF]

, 2017
The most frequent disease of the locomotor system is osteoarthritis (OA), which, as a chronic joint disease, might benefit more from nutrition than acute illnesses.
Gazova, Zuzana, Kordelle, Jens, Lochnit, Guenter, Schadow, Saskia, Siebert, Hans-Christian, Simons, Viktor S., Steinmeyer, Juergen   +6 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Geochemical Characteristics of Selenium in Surface Soil of Central Townships in Zhaojue County, Sichuan Province

Yankuang ceshi, 2022
BACKGROUND Selenium (Se) is one of the essential trace elements for humans, and an important way for humans to obtain and supplement selenium is by eating natural selenium-enriched agricultural products. The geochemical characteristics of selenium in the
ZHAO Chen, SUN Binbin, HE Ling, WU Chao, CHENG Xiaomeng, ZENG Daoming, LIU Dong   +6 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Innovation and Development for Atomic Fluorescence Spectrometry Analysis

Yankuang ceshi, 2013
Atomic fluorescence spectrometry (AFS) has such characteristics of chemical vapor separation and non dispersive optical system. It is one of the most successful analytical methods available to determine trace As, Sb, Bi, Hg, Se, Te and Ge elements ...
LI Gang, HU Si-xian, CHEN Lin-ling
doaj