Results 31 to 40 of about 1,073,150 (315)
Case Studies in Construction Materials, 2023 In order to explore the effect of oyster shell powder on the mechanical properties of asphalt, in order to explore the modification mechanism of oyster shell powder on asphalt, based on matrix asphalt, this paper prepared oyster shell powder modified ...
Chao Hu, Daojun Zhong, Shilong Li
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Atomic inner-shell radiation seeded free-electron lasers
Physical Review Accelerators and Beams, 2018 In order to effectively improve the output quality of x-ray free electron laser (XFEL), we theoretically propose an XFEL scheme seeded by atomic inner-shell laser.
Han Zhang +4 more
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Computer simulation of the Cu@Si core-shell nanoparticles formation [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2018 In this work computer simulation of the condensation processes of Cu-Si core-shell nanoparticles was performed by the molecular dynamics method. It was shown that simultaneous cooling of atomic vapors of copper and silicon leads to the formation of ...
V.S. Baidyshev
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Nature Communications, 2018 Atomic shell closure and electronic shell closure are generally considered to be competing effects in stabilizing magic-sized metal nanoclusters. Here, the authors show, by co-crystallizing two differently-sized clusters, that both mechanisms can work ...
Juanzhu Yan +8 more
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