Results 71 to 80 of about 1,353,139 (279)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cowan Code: 50 Years of Growing Impact on Atomic Physics

open access: yesAtoms, 2019
The famous Cowan’s book, “The Theory of Atomic Structure and Spectra”, published in 1981, and his suite of computer codes based on it, continue to be highly influential in atomic physics and many other research areas.
Alexander Kramida
doaj   +1 more source

Magnetic anisotropies of late transition metal atomic clusters

open access: yes, 2007
We analyze the impact of the magnetic anisotropy on the geometric structure and magnetic ordering of small atomic clusters of palladium, iridium, platinum and gold, using Density Functional Theory.
Fernández-Seivane, Lucas, Ferrer, Jaime
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Local Lattice Distortion Caused by Short Range Charge Ordering in LiMn$_2$O$_4$

open access: yes, 2013
We have performed powder neutron diffraction on $^7$Li-enriched sample of LiMn$_2$O$_4$ at 300 K. The crystal structure determined by Rietveld analysis is a cubic spinel with space group of $Fd\bar{3}m$ in which all Mn atoms are crystallograghically ...
Igawa, Naoki   +7 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Recent progress in atomically precise Ag/Cu-based hydride clusters

open access: yesPolyoxometalates
Owing to advantages in synthesis, separation, structure determination, and low cost (compared to noble metal nanoclusters), Ag/Cu hydride clusters (and their alloys) have received increasing research interest in recent decades and have shown great ...
Ying Lv   +4 more
doaj   +1 more source

Electron tomography at 2.4 {\AA} resolution

open access: yes, 2012
Transmission electron microscopy (TEM) is a powerful imaging tool that has found broad application in materials science, nanoscience and biology(1-3). With the introduction of aberration-corrected electron lenses, both the spatial resolution and image ...
Chen, Chien-Chun   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Circuit complexity of quantum access models for encoding classical data

open access: yesnpj Quantum Information
How to efficiently encode classical data is a fundamental task in quantum computing. While many existing works treat classical data encoding as a black box in oracle-based quantum algorithms, their explicit constructions are crucial for the efficiency of
Xiao-Ming Zhang, Xiao Yuan
doaj   +1 more source

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