Results 71 to 80 of about 882,221 (292)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Surface contribution to the anisotropy of magnetic nanoparticles

open access: yes, 2002
We calculate the contribution of the Neel surface anisotropy to the effective anisotropy of magnetic nanoparticles of spherical shape cut out of a simple cubic lattice.
D. A. Garanin, H. Kachkachi, L. Néel
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Synergistic effect of Nb and Ta alloying on microstructure and mechanical properties of CoCrFeNi high-entropy alloy

open access: yesCailiao gongcheng
CoCrFeNi-(Nb, Ta) high-entropy alloys (HEAs) were prepared by a vacuum arc melting process, and the synergistic effect of Nb and Ta concentrations on the microstructure evolution and mechanical properties was investigated in detail.
ZHU Zhe   +7 more
doaj   +1 more source

Cryogenic-temperature-induced structural transformation of a metallic glass

open access: yesMaterials Research Letters, 2017
The plasticity of metallic glasses depends largely on the atomic-scale structure. However, the details of the atomic-scale structure, which are responsible for their properties, remain to be clarified. In this study, in-situ high-energy synchrotron X-ray
Xilei Bian   +8 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Does the Intra‐Atomic Deformation Energy of Interacting Quantum Atoms Represent Steric Energy?

open access: yesChemistryOpen, 2019
We show that the mutual, through‐space compression of atomic volume experienced by approaching topological atoms causes an exponential increase in the intra‐atomic energy of those atoms, regardless of approach orientation. This insight was obtained using
Benjamin C. B. Symons   +4 more
doaj   +1 more source

Direct Probing of 1/f Noise Origin with Graphene Multilayers: Surface vs. Volume

open access: yes, 2012
Low-frequency noise with the spectral density S(f)~1/f^g (f is the frequency and g~1) is a ubiquitous phenomenon, which hampers operation of many devices and circuits. A long-standing question of particular importance for electronics is whether 1/f noise
Balandin, Alexander A.   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Atomic Charges and Chemical Bonding in Y-Ga Compounds

open access: yesCrystals, 2018
A negative deviation from Vegard rule for the average atomic volume versus yttrium content was found from experimental crystallographic information about the binary compounds of yttrium with gallium.
Yuri Grin   +3 more
doaj   +1 more source

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