Results 41 to 50 of about 28,265 (262)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Word-level Symbolic Trajectory Evaluation
, 2015 Symbolic trajectory evaluation (STE) is a model checking technique that has been successfully used to verify industrial designs. Existing implementations of STE, however, reason at the level of bits, allowing signals to take values in {0, 1, X}.
C-JH Seger +8 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Atomization and mixing study [PDF]
The state of the art in atomization and mixing for triplet, pentad, and coaxial injectors is described. Injectors that are applicable for LOX/hydrocarbon propellants and main chamber and fuel rich preburner/gas generator mixture ratios are of special ...
Ferrenberg, A., Jaqua, V. W.
core +1 more source
The Influence of geometrical and operational parameters on internal flow characteristics of Internally Mixing Twin-Fluid Y-Jet Atomizers [PDF]
, 2019 Internally mixing twin-fluid Y-jet atomizers are widely used in coal fired thermal power plants for start-up, oil-fired thermal power plants and industrial boilers.
Ehmann, M. +3 more
core +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Effect of cavitation on velocity in the near-field of a diesel nozzle
, 2015 The entire process of atomization of the fuel in an internal combustion engine plays a very important role in determining the overall efficiency of these engines.
Blaisot, Jean-Bernard +6 more
core +1 more source
A real-space grid implementation of the Projector Augmented Wave method [PDF]
, 2004 A grid-based real-space implementation of the Projector Augmented Wave (PAW) method of P. E. Blochl [Phys. Rev. B 50, 17953 (1994)] for Density Functional Theory (DFT) calculations is presented.
C. Berghold +8 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Fluorine-hydrogen performance evaluation. Phase I, part I - Analysis, design, and demonstration of high performance injectors for the liquid fluorine-gaseous hydrogen combination Final report [PDF]
Analysis, design, and demonstration of high performance injectors for liquid fluorine- gaseous hydrogen propellant ...
Arbit, H. A., Clapp, S. D.
core +1 more source