Results 51 to 60 of about 787,470 (297)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

catena-Poly[[[tetraaquacadmium(II)]-μ-4,4′-bipyridine] fumarate tetrahydrate]

open access: yesActa Crystallographica Section E, 2008
In the crystal structure of the title compound, [Cd(C10H8N2)(H2O)4](C4H2O4)·4H2O, the CdII atom, on an inversion centre, is six-coordinated by four O atoms from four water molecules and two N atoms from 4,4′-bpy molecules in a distorted ...
Ya-Ru Pan
doaj   +1 more source

Solid phases and pairing in a mixture of polar molecules and atoms

open access: yes, 2010
We consider a mixture of hard core bosonic polar molecules, interacting via repulsive dipole-dipole interaction, and one atomic bosonic species. The mixture is confined on a two-dimensional square lattice and, at low enough temperatures, can be described
Capogrosso-Sansone, B.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Comparison of the CH and OH Groups as Proton Donors within Hydrogen Bonds

open access: yesChemistryEurope
The ability of the CH group to act as proton donor is now widely accepted, even if the H bonds (HBs), which it forms are typically much weaker than those of the hydroxyl group, particularly for a sp3‐hybridized C.
Savannah Rawlings, Steve Scheiner
doaj   +1 more source

catena-Poly[[[diaquairon(II)]-μ-pyridine-2,5-dicarboxylato-[tetraaquairon(II)]-μ-pyridine-2,5-dicarboxylato] tetrahydrate]

open access: yesActa Crystallographica Section E, 2008
In the crystal structure of the title compound, {[Fe2(C7H3NO4)2(H2O)6]·4H2O}n, there are two types of coordination for the FeII atoms.
Bao-Guo Guo   +4 more
doaj   +1 more source

Fortran 90 implementation of the Hartree-Fock approach within the CNDO/2 and INDO models

open access: yes, 2008
Despite the tremendous advances made by the ab initio theory of electronic structure of atoms and molecules, its applications are still not possible for very large systems.
Abdurahman   +31 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Uptake of gases in bundles of carbon nanotubes

open access: yes, 2000
Model calculations are presented which predict whether or not an arbitrary gas experiences significant absorption within carbon nanotubes and/or bundles of nanotubes. The potentials used in these calculations assume a conventional form, based on a sum of
A. Chambers   +49 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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