Results 71 to 80 of about 787,470 (297)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Interacting Quantum Atoms Analysis of Covalent and Collective Interactions in Single Elongated Carbon–Carbon Bonds

Molecules
Chemical bonds among carbon atoms are central to chemistry. A general working principle regarding these interactions is that these contacts become stronger as the carbon atoms become closer to each other. Nevertheless, there are long, yet strong single C–
Antonio Bonesana-Espinoza, José Manuel Guevara-Vela, Evelio Francisco, Tomás Rocha-Rinza, Ángel Martín Pendás   +4 more
doaj   +1 more source

Simultaneous deceleration of atoms and molecules in a supersonic beam

New Journal of Physics, 2015
A unique property of Zeeman effect based manipulation of paramagnetic particle’s motion is the ability to control velocities of both atoms and molecules.
Nitzan Akerman, Michael Karpov, Liron David, Etay Lavert-Ofir, Julia Narevicius, Edvardas Narevicius   +5 more
doaj   +1 more source

Extension of the Schiff theorem to ions and molecules

, 2011
According to the Schiff theorem the nuclear electric dipole moment (EDM) is screened in neutral atoms. In ions this screening is incomplete. We extend a derivation of the Schiff theorem to ions and molecules.
A. Kozlov, B. E. Sauer, K. P. Huber, O. P. Sushkov, O. P. Sushkov, O. P. Sushkov, V. V. Flambaum, V. V. Flambaum, V. V. Flambaum   +8 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Crystal structure of 6-(4-chlorophenyl)-6a-nitro-6a,6b,8,9,10,12a-hexahydro-6H,7H-spiro[chromeno[3,4-a]indolizine-12,11′-indeno[1,2-b]quinoxaline]

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C35H27ClN4O3, crystallized with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran and pyridine rings adopt envelope and chair conformations, respectively.
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, D. Velmurugan, J. Nagasivarao   +4 more
doaj   +1 more source

Quantum rainbow scattering at tunable velocities

, 2012
Elastic scattering cross sections are measured for lithium atoms colliding with rare gas atoms and SF6 molecules at tunable relative velocities down to ~50 m/s. Our scattering apparatus combines a velocity-tunable molecular beam with a magneto-optic trap
B. Ruff, F. Stienkemeier, H. Metcalf, I. W. Smith, M. Mudrich, M. Strebel, R. B. Bernstein, R. Krems, T.-O. Müller   +8 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Diaquadimethanolbis[4-(1H-tetrazol-1-yl)benzoato]zinc(II) dihydrate

Acta Crystallographica Section E, 2008
In the title compound, [Zn(C8H5N4O2)2(CH3OH)2(H2O)2]·2H2O, the ZnII ion lies on an inversion centre and is coordinated by two O atoms from two 4-(tetrazol-1-yl)benzoate ligands, two O atoms from two methanol molecules and two O atoms from two water ...
Shu-Ming Zhang
doaj   +1 more source

Electron Spins in Artificial Atoms and Molecules for Quantum Computing

, 2002
Achieving control over the electron spin in quantum dots (artificial atoms) or real atoms promises access to new technologies in conventional and in quantum information processing. Here we review our proposal for quantum computing with spins of electrons
Anderson P W, Averin D V, Awschalom D D, Burkard G, Ciorga M, Daniel Loss, DiVincenzo D P, Golovach V N, Gupta J A, Hewson A C, Kouwenhoven L P, Kouwenhoven L P, Kouwenhoven L P, Mahan G D, Nielsen M A, Peres A, Preskill J, Shankar R, Shor P W, Shor P W, Vitaly N Golovach, Wegewijs M R   +21 more
core   +1 more source