Results 41 to 50 of about 53,043 (267)

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

Epilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan, Beatrice Southby Goad, Meagan Allen, Jill Rodda, Kay L. Richards, Simone L. Ardern‐Holmes, Daniel Bamborschke, Daniel Fritzen, Inna Hughes, Kate Riney, Ana Roche Martinez, Angelo Russo, Adriane Sinclair, Stefano Sartori, Marina Trivisano, Angela De Dominicis, Nicola Specchio, Rikke S. Møller, Ingrid E. Scheffer, Walid Fazeli, Markus Wolff, Steven Petrou, Katherine B. Howell, Géza Berecki   +23 more
wiley   +1 more source

Class and social inequality in Ian Mcewan’s Atonement

Journal of Contemporary Philology, 2020
Atonement, perhaps Ian McEwan’s best-known novel, is considered an epic of British postmodernist literature because it touches on a variety of contemporary topics.
Vasko Talevski
doaj   +1 more source

Kataphysical inquiry, onto-relationality and elemental forms in T.F. Torrance’s doctrine of the mediation of Jesus Christ

In die Skriflig, 2013
The doctrine of the mediation of Jesus Christ in the scientific theology of T.F. Torrance rests on the fundamental methodological axiom that knowledge is developed according to the nature (kata physin) of the object of scientific inquiry.
Martin M. Davis
doaj   +1 more source

Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring

Epilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury, Ingmar Blümcke, Robyn M. Busch, Balu Krishnan, Juan Bulacio, William Bingaman, Demitre Serletis, Imad Najm   +7 more
wiley   +1 more source

The Multifaceted Work of Christ: Herman Bavinck’s Doctrine of Atonement as Both Corrective and Retrieval

Perichoresis: The Theological Journal of Emanuel University
This essay examines Herman Bavinck’s doctrine of atonement within his treatment of Christ’s humiliation in volume three of his Reformed Dogmatics. Through an investigation of Bavinck’s critiques of key nineteenth century theologians and of Bavinck’s own ...
Crosby Sarah Killam
doaj   +1 more source

The Pauline Model of Atonement in Romans 3:19-31 [PDF]

, 2012
The Pauline model of Romans 3:19-31 is a description of substitutionary atonement. Sin, guilt, righteousness, faith in Christ, justification, redemption, propitiation, Christ a covering, atonement in his blood, substitute, justice, justifier, and the ...
Mathers, Norm
core  

Characterizing early behavioral and social–emotional problems in young children with SCN1A+ Dravet syndrome: Findings from the ENVISION prospective natural history study

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is the prototypic developmental and epileptic encephalopathy, characterized by drug‐resistant seizures, developmental slowing, and many other morbidities. Detailed characterization of behavioral phenotypes and social–emotional skill development are limited.
Ingrid E. Scheffer, M. Scott Perry, Joseph Sullivan, Susana Boronat, James Wheless, Andreas Brunklaus, Linda Laux, Anup D. Patel, Colin Roberts, Dennis Dlugos, Deborah Holder, Kelly Knupp, Matt Lallas, Steven Phillips, Eric Segal, Dennis Lal, Elaine Wirrell, Sameer M. Zuberi, Rebecca Shaffer, Mary Wojnaroski, Madison M. Berl, Sarah Christensen, Emma S. James, Maria Candida Vila, Norman Huang, Jacqueline S. Gofshteyn, Salvador Rico   +26 more
wiley   +1 more source

An Atonement Problem for Contradictory Christology

TheoLogica
Recently, Jc Beall has advanced a model of the incarnation according to which one can reconcile the apparently incompatible attributes attributed to Christ by taking them as true contradictions.
Drew Smith
doaj   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

Epilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing, Lirong Han, Dongjun Guo, Thomas J. Foutz, Michael Wong   +4 more
wiley   +1 more source

Jesus as the Pattern of Love in Atonement

St Andrews Encyclopaedia of Theology, 2023
This article discusses the interpretation of the Christian doctrine of atonement which is usually called the ‘moral influence’ theory. A close analysis will suggest that this theory is better called ‘persuasive love’, since the revelation of God’s love ...
Paul Fiddes
doaj