Results 311 to 320 of about 348,699 (383)

Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis

Allergy, EarlyView.
This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino, Juno Kim, Manru Li, Philipp Gessner, Patrick Westermann, Yagız Pat, Carina Beha, Claudia Traidl‐Hoffmann, Jeremy Bost, Nicolas Gaudenzio, Christoph B. Messner, Cezmi A. Akdis, Yasutaka Mitamura   +12 more
wiley   +1 more source

Risk of atopic dermatitis in periodontitis patients with and without dental scaling: A retrospective cohort study. [PDF]

PLoS One
Chiang MC, Chang CC, Lee CY, Yeh CC, Huang YC, Chen TL, Liao CC.   +6 more
europepmc   +1 more source

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

Allergy, EarlyView.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller, Celeste M. Boesjes, Roselie A. Achten, Lisa A. Beck, Alan D. Irvine, Christian Vestergaard, Marlies de Graaf, Femke van Wijk, Daphne S. Bakker, Stephan Weidinger   +9 more
wiley   +1 more source

An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents

Allergy, EarlyView.
Eckard Hamelmann, Bianca Schaub, Susanne Lau, Leonard B. Bacharier   +3 more
wiley   +1 more source

Subcutaneous Allergen Immunotherapy in Adults Allergic to House Dust Mites: A Phase 3 Randomized Controlled Trial

Allergy, EarlyView.
SCIT at 50,000 AUeq/mL is safe and demonstrates clinically meaningful efficacy in patients with moderate to severe HDM‐induced allergic rhino‐conjunctivitis. Clinically relevant efficacy was observed in the moderate to severe group, but not in the overall study population, likely due to the inclusion of many patients with only mild symptoms. Safety and
Claus Bachert, Hans Hoogeveen, Rimko ten Have, Donghui Yu, Margitta Worm, Oliver Pfaar, Marek Jutel, Andreas Distler, Andrzej Bozek, Dirk‐Jan Opstelten, Annemie Narkus, Ronald van Ree   +11 more
wiley   +1 more source

Nutritional Status and Severity of Atopic Dermatitis in Children in a Hospital Setting in Kinshasa, Democratic Republic of the Congo. [PDF]

Clin Cosmet Investig Dermatol
Matandoko LM, Seudjip LJN, Kayembe DK, Bunga PM, Paku SM.   +4 more
europepmc   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

From Disease Control to Disease Modification: The Atopic Dermatitis Disease Activity Index

Allergy, EarlyView.
Thomas Bieber, Laura Maintz, Ganesh E. Phad, Marie‐Charlotte Brüggen   +3 more
wiley   +1 more source

Genome Sequences and Antifungal Susceptibility of Candida auris from a Patient with Atopic Dermatitis. [PDF]

Mycopathologia
Kim T, Bae M, Bang J, Jeon J, Cho YJ, Park J, Jung WH.   +6 more
europepmc   +1 more source