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Multi-omic triangulation identifies molecular candidates of atopic dermatitis severity

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Watts K   +69 more
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Atopic Dermatitis

Pediatrics In Review, 1994
Introduction Atopic dermatitis, also referred to as atopic eczema, infantile eczema, allergic eczema, disseminated neurodermatitis, and prurigo Besnier, is a common and important cause of morbidity in children of all ages. A total of 22% of patients seen in pediatric dermatology clinics have atopic dermatitis.
C S, Lapidus, P J, Honig
  +7 more sources

Atopic Dermatitis

Primary Care: Clinics in Office Practice, 2023
Atopic dermatitis (AD) is a common, chronic relapsing, and remitting inflammatory skin disease that is characterized by erythematous, scaly, and pruritic lesions often located over the flexural surfaces. Treatment goals of AD include the reduction of itching and burning, as well as the reduction of skin changes.
Karl T, Clebak   +4 more
openaire   +3 more sources

Atopic dermatitis

Journal of the American Academy of Dermatology, 2005
Atopic dermatitis (AD) is an eczematous, highly pruritic chronic inflammatory skin disease. It usually begins early in life and often occurs in people with a personal or family history of asthma and allergic rhinitis. The prevalence is high, especially in children,and it has been rising in recent decades, in parallel with asthma prevalence. Although AD
Eric L, Simpson, Jon M, Hanifin
openaire   +5 more sources

Atopic Dermatitis

Allergy and Asthma Proceedings, 1990
AD is a complex, multifactorial, cutaneous manifestation of the atopic diathesis. Observations from bone marrow transplantation cases have shown transmission of the disease from atopic donors [30] and indicate that the basic defect is carried in immune and inflammatory cells which infiltrate skin lesions.
Jonathan Bernstein   +3 more
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Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials

British Journal of Dermatology, 2020
Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced atopic dermatitis (AD) severity in a phase II study with concomitant topical corticosteroids.
E. Simpson   +23 more
semanticscholar   +1 more source

Atopic dermatitis

Journal of the American Academy of Dermatology, 1981
Atopic dermatitis is a chronically relapsing inflammatory skin disease with altered immune and pharmacologic responses. Elevated serum IgE probably reflects defective immune regulation. Various other cellular immune defects rise and fall exacerbations and remissions of skin inflammation.
openaire   +4 more sources

Atopic dermatitis

The Lancet, 2016
Atopic dermatitis (also known as atopic eczema) is a chronic inflammatory skin disease that is characterised by intense itching and recurrent eczematous lesions. Although it most often starts in infancy and affects two of ten children, it is also highly prevalent in adults.
Stephan, Weidinger, Natalija, Novak
openaire   +3 more sources

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