<i>Strongyloides stercoralis</i> Infection and Spirometry-Defined Airway Obstruction in Children with Sickle Cell Disease: A Species-Specific Multicentre Cross-Sectional Study in French Guiana. [PDF]
Bafunyembaka G +5 more
europepmc +1 more source
ABSTRACT Genome‐wide association studies (GWAS) have uncovered multiple loci associated with atopic dermatitis (AD), although mechanistic understanding remains limited. Here, we examine a risk variant in the aquaporin 3 (AQP3) promoter and propose a mechanistic link between genotype to altered autophagy, skin barrier integrity, and wound healing in AD.
Yi Ying Eliza Lim +5 more
wiley +1 more source
Allergy in Latin America: Great Need, Even Greater Opportunity. [PDF]
Borzutzky A +3 more
europepmc +1 more source
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease with significant physical and psychosocial burden. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has proven to be effective for moderate‐to‐severe AD, but long‐term real‐world data remain limited.
Francesco Leo +11 more
wiley +1 more source
Follow-up study on factors influencing the persistence of asthma in discharged children. [PDF]
Zou H, Han P, Yin J, Shen K.
europepmc +1 more source
When to consider an inborn error of immunity: clues for physicians
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, Volume 81, Issue 9, Page 3377-3383, September 2026.
Jaime Bernaola +14 more
wiley +1 more source
Update on biologic and small molecules treatments in pediatric allergic diseases
This graphical abstract summarizes key targets, mechanisms of action, and indications of biologic and small molecules treatments in pediatric allergic diseases.abbreviations : BAS, basophil; BTK, Bruton tyrosine kinase; cDC, conventional dendritic cell; IgE, immunoglobulin E; FCER1, high affinity IgE receptor; IL, interleukin; IL4R, IL4 receptor; JAK ...
Herman T. den Dekker +10 more
wiley +1 more source
Paediatric perioperative hypersensitivity reactions: Analysis of the French GERAP network database
Graphical abstract of the pediatric perioperative hypersensitivity reactions recorded in the GERAP network datbase between 1997 and 2024. Abstract Background Perioperative hypersensitivity (POH) reactions are rare but potentially life‐threatening and remain poorly characterised in children.
Mertes Paul Michel +104 more
wiley +1 more source
Triggers, clinical spectra and outcomes of pediatric anaphylaxis in a tertiary center: impact of comorbidities and cofactors on severity. [PDF]
Keser-Ozturk N +12 more
europepmc +1 more source

