Results 201 to 210 of about 345,803 (325)
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis. [PDF]
Sui Y +16 more
europepmc +1 more source
Valorização de recursos genéticos endógenos através das sinergias multi-ator: O caso do programa VASO 2.0 [PDF]
Mendes Moreira, P +3 more
openalex +1 more source
Low‐intervention clinical trials in Spain: Do they progress?
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza +4 more
wiley +1 more source
Effects of dengue virus type-2 serotype (DENV-2) on the expression profile of matrix metalloproteinases in THP-1, monocyte cells and their roles in endothelial dysfunctions: protective effect of atorvastatin. [PDF]
Niranjan R +4 more
europepmc +1 more source
ABSTRACT How do wineries design sustainability practices and use environmental management accounting (EMA)? This study addresses that question by analyzing the influence of contingency factors on the adoption of sustainability practices and the use of EMA tools to improve the environmental performance of wineries. The research was carried out through a
Andréia Cittadin +2 more
wiley +1 more source
First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies. [PDF]
Carneiro A +7 more
europepmc +1 more source
This work presents a curated DNA barcode reference library covering 147 species of longhorned beetles commonly intercepted in European biosurveillance programmes. By focusing on taxonomic validation and data quality, this resource improves the accuracy of specimen identification despite the limitations of existing databases. It also supports ecological
Loïs Veillat +11 more
wiley +1 more source

