Results 201 to 210 of about 24,800 (286)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Atorvastatin enhances LDL receptor-mediated LDL-C uptake and modulates PCSK9 protein expression in pancreatic β-cells. [PDF]

Islets
Zhang Z, Zheng H, Zhang L, Su P, Chen X, Xiang A, Yang J, Guan H, Fan J, Yu Q.   +9 more
europepmc   +1 more source

Smaller hamstrings autograft size after primary ACL reconstruction is associated with higher odds for graft failure: A meta‐analysis on autografts sizes covering 46,268 patients

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 9, Page 3212-3232, September 2026.
Abstract Purpose To investigate the association between autograft size and graft failure for hamstrings tendon (HT), patellar tendon (PT) and quadriceps tendon (QT) autografts. Methods Medline, PubMed, Cochrane Library, Embase, Amed and Web of Science were searched at four separate time points, with the most recent search in February 2025.
Rebecca Hamrin Senorski, Johan Högberg, Kevin Teow, Anna Nordenholm, Janina Kaarre, Thorkell Snaebjörnsson, Volker Musahl, Kristian Samuelsson, Eric Hamrin Senorski   +8 more
wiley   +1 more source

Synthesis and Evaluation of the Effects of Nanoparticles of Atorvastatin and Atorvastatin on Cuprizone-Induced Demyelination: Modulation of the Nrf2/NF-kB Signaling Pathway. [PDF]

Iran J Pharm Res
Shirooie S, Heidarizade N, Noori T, Sureda A, Iranpanah A, Alibeygi S.   +5 more
europepmc   +1 more source

Genotype‐by‐Environment Interaction Influenced the Crude Protein and Total Amino Acid Content in Lentil Varieties

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Lentil (Lens culinaris Medik.) is a globally important grain legume valued for its high‐protein content and nutritional quality. However, the genetic and environmental factors influencing protein and amino acid composition, particularly the role of genotype × environment interaction (GEI), remain partially uncovered.
Alex Kumi Frimpong, Anastasiya Kuhalskaya, Lorenzo Rocchetti, Giacomo Conti, Asia Cicconi, Chiara Santamarina, Francesca Francioni, Benedetta Fanesi, Tania Gioia, Stefania Marzario, Alice Pieri, Giulia Frascarelli, Elisa Bellucci, Laura Nanni, Deborah Pacetti, Roberto Papa, Elena Bitocchi, Valerio Di Vittori   +17 more
wiley   +1 more source

Short-term effect of atorvastatin on renal oxidative stress, inflammation, and fibrosis in a rat model of streptozotocin-induced diabetes. [PDF]

J Diabetes Metab Disord
Mayyas F.
europepmc   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao, Honghua Zhang, Jingyu Chen, Ziyu Qian, Ning Zhang, Yihua Zhang, Hui Ye, Jianbing Wu, Zhangjian Huang   +8 more
wiley   +1 more source

Habitat loss reshuffles ecological and evolutionary interactions in a seed dispersal network

Oikos, Volume 2026, Issue 9, September 2026.
In tropical forests, habitat loss reshapes species composition, favoring generalists and recently emerged lineages while specialists and older evolutionary lineages are lost. However, how changes in species ecological attributes and evolutionary history affect ecological processes is poorly explored.
Fernando César Gonçalves Bonfim, Mauro Galetti, Elaine Rios, Cynthia Oliveira, Milena Gama, Ketlen Bona, Geanne Carla Novais‐ Pereira, Thiago de Castro Ribeiro, Eliana Cazetta   +8 more
wiley   +1 more source

Impact of Ambient Artificial Intelligence Documentation on Cognitive Load. [PDF]

Mayo Clin Proc Digit Health
Hudson TJ, Albrecht M, Smith TR, Ator GA, Thompson JA, Shah T, Shanks D.   +6 more
europepmc   +1 more source

A simple probabilistic AlphaFold interaction score

Protein Science, Volume 35, Issue 9, September 2026.
Abstract AlphaFold has enabled large‐scale prediction of protein–protein and protein–nucleic acid complexes, but ranking and assessing the quality of predicted models remain challenging. Existing confidence scores are often highly parametrized and provide limited interpretability.
Mihaly Badonyi, Agnes Toth‐Petroczy
wiley   +1 more source