Results 311 to 320 of about 127,756 (395)

Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease

open access: yesDrug Metabolism And Disposition, 2011
Rhiannon N Hardwick   +4 more
semanticscholar   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen   +4 more
wiley   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

The ATP‐binding cassette transporter–encoding gene CgSNQ2 is contributing to the CgPDR1‐dependent azole resistance of Candida glabrata

open access: yesMolecular Microbiology, 2008
R. Torelli   +6 more
semanticscholar   +1 more source

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell

open access: yesMolecular Microbiology, EarlyView.
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez   +13 more
wiley   +1 more source

AtMRP1 gene of Arabidopsis encodes a glutathione S-conjugate pump: isolation and functional definition of a plant ATP-binding cassette transporter gene.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1997
Yu-ping Lu, Ze-Sheng Li, P. A. Rea
semanticscholar   +1 more source

The maize mitogen‐activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance

open access: yesNew Phytologist, EarlyView.
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong   +8 more
wiley   +1 more source

Selective magnetic resonance imaging of antibiotic-resistant bacteria leveraging ATP-binding cassette sugar transporter-responsive probes

open access: gold
Yao He   +9 more
openalex   +1 more source

Circular RNA Vv‐circCOR27 modulates thermotolerance through attenuating VvHSP90.2b‐VvHsfA7a interaction in grapevine

open access: yesNew Phytologist, EarlyView.
Summary Circular RNAs (circRNAs) are single‐stranded, covalently closed RNA molecules that arise from exon back‐splicing. The identification and function investigation of circRNAs have been comprehensively explored in plants, however, the regulatory mechanisms are largely unknown.
Yi Ren   +14 more
wiley   +1 more source

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