Results 341 to 350 of about 156,745 (364)

ATP-binding cassette transporters in human heart failure

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008
Adenosine triphosphate-binding cassette (ABC) transporters are involved in energy-dependent transport of substrates across biological membranes. We hypothesized that their expression is altered during human heart failure, suggesting a pathophysiologic basis.
Thomas F. Solbach, Thomas Eschenhagen, Martin F. Fromm, Oliver Zolk, Michael Weyand, Barbara Paulus   +5 more
openaire   +3 more sources

ATP-binding cassette transporter A1 and cholesterol trafficking

Current Opinion in Lipidology, 2002
Two hallmarks of cardiovascular disease are the presence of sterol-laden macrophages in the artery wall and reduced plasma HDL levels. A cell membrane protein named ATP-binding cassette transporter A1 (ABCA1) mediates secretion of excess cholesterol from cells into the HDL metabolic pathway.
openaire   +3 more sources

Pharmacogenetics of ATP-Binding Cassette Transporters and Clinical Implications

2009
Drug resistance is a severe limitation of chemotherapy of various malignancies. In particular efflux transporters of the ATP-binding cassette family such as ABCB1 (P-glycoprotein), the ABCC (multidrug resistance-associated protein) family, and ABCG2 (breast cancer resistance protein) have been identified as major determinants of chemoresistance in ...
Ingolf Cascorbi, Sierk Haenisch
openaire   +3 more sources

Hormonal regulation of ATP binding cassette transporters

2004
Although the knowledge of ATP-binding cassette of lipid transport had grown substantially over the last few years, the detailed molecular mechanisms and the exact functions of these transporters were still awaiting clarification. In this thesis, analysis of the actions of human steroid and non-steroid hormones on cholesterol and phospholipid effluxes ...
openaire   +2 more sources

Reversing Agents for ATP-Binding Cassette Drug Transporters

2009
The multidrug resistance (MDR) phenotype exhibited by cancer cells is believed to be the major barriers to successful chemotherapy in cancer patients. The major form of MDR phenotype is contributed by a group of ATP-binding cassette (ABC) drug transporters which include P-glycoprotein, multidrug resistance-associated protein 1, and breast cancer ...
openaire   +3 more sources

Structure and Function of Hepatobiliary ATP Binding Cassette Transporters

Chemical Reviews, 2021
Lutz Schmitt, Sander H J Smits, Liqun Xu
exaly  

Adjustable breathing resistance for laryngectomized patients: Proof of principle in a novel heat and moisture exchanger cassette

Head and Neck, 2021
Maartje Leemans, Michiel W M Van Den Brekel, Shivakumar Thiagarajan   +2 more
exaly  

The human ATP‐binding cassette (ABC) transporter superfamily

Human Mutation, 2022
Michael Dean, Karobi Moitra, Rando Allikmets   +2 more
exaly  

Influence of different influence parameters on mixing characteristics of silicon particles in cassette

International Journal of Chemical Reactor Engineering, 2023
Hanlin Sun
exaly  

Ins and outs of the ATP-binding cassette transporter A1

Current Opinion in Lipidology, 2016
Yury I. Miller, Dmitri Sviridov
openaire   +3 more sources