First report of ATP2A2 somatic mosaicism occurring during embryogenesis in transient acantholytic dermatosis [PDF]
JEADV Clinical PracticeTransient acantholytic dermatosis (TAD) is a relatively common skin disease that typically affects older individuals, which shows clinical and histologic similarities to autosomal dominant Darier disease.
Emi Hiromatsu +6 more
doaj +2 more sources
Dominant rhabdomyolysis linked to a recurrent ATP2A2 variant reducing SERCA2 function in muscle [PDF]
BrainAbstract Rhabdomyolysis is an acute failure of cellular homeostasis resulting in muscle breakdown, triggered by trauma, infection, drugs or strenuous exercise. Recurrent rhabdomyolysis is often associated with genetic and metabolic defects of skeletal muscle.
Sivasankar Malaichamy +32 more
openalex +5 more sources
ATP2A2 Mutations in Darier's Disease and Their Relationship to Neuropsychiatric Phenotypes [PDF]
Human Molecular Genetics, 1999 Darier's disease (DD) is a rare, dominantly inherited disorder that affects the skin producing a variety of types of lesion. Close examination of lesional DD skin shows the presence of abnormal keratinization (epidermal differentiation) and acantholysis (loss of cohesion) of keratinocytes.
Nick Jacobsen +7 more
openalex +3 more sources
Mutations in ATP2A2 in Patients with Darier's Disease [PDF]
Journal of Investigative Dermatology, 2003 Shigaku Ikeda +5 more
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MicroRNA-200c-3p Negatively Regulates ATP2A2 and Promotes the Progression of Papillary Thyroid Carcinoma [PDF]
Biochemical Genetics, 2022 microRNA-200c-3p (miR-200c-3p) has emerged as an important tumor growth regulator. However, its function in papillary thyroid carcinoma (PTC) is poorly understood. This study was conducted to investigate the role of miR-200c-3p in the progression of human PTC. The miR-200c-3p expression in human PTC tissues and cell lines was evaluated.
Yu-Lai Feng +4 more
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Comparative Analyses of Gene and Protein Expressions and the Lipid Contents in Intramuscular and Subcutaneous Fat Tissues in Fattening Steers [PDF]
AnimalsIn this study, we aimed to characterize intramuscular fat (IMF) tissue in fattening steers through a comparison with subcutaneous fat (SCF) tissue. The IMF of the longissimus thoracis et lumborum and the SCF of the back fat from three fattening steers ...
Kaixi Ji +4 more
doaj +2 more sources
Effects of cardiac decellularized extracellular matrix hydrogel as a functional myocardial patch on the growth of cardiomyocytes [PDF]
BioMedical Engineering OnLineObjectives To address the immune rejection and inflammatory reactions that currently exist in functional myocardial patches when promoting myocardial cell growth.
Jun Hu, Wei Xiao
doaj +2 more sources
The role of Atp2a2-mediated calcium imbalance and endoplasmic reticulum stress in hydrocortisone-induced neurotoxicity. [PDF]
Cell Stress ChaperonesKong W +5 more
europepmc +2 more sources