Results 61 to 70 of about 2,278 (176)

“Clinical Overlap of Darier's Disease and Acrokeratosis Verruciformis of Hopf”: A Case Report

Clinical Case Reports
Darier's disease and Acrokeratosis Verruciformis of Hopf can exhibit overlapping clinical features due to mutations in the same ATP2A2 gene. Recognizing this genetic and phenotypic overlap is crucial for accurate diagnosis, genetic counseling, and ...
Mahesh Mathur, Sumit Paudel, Sandhya Regmi, Sambidha Karki, Shilpa Maharjan, Nabita Bhattarai   +5 more
doaj   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Morbus Darier und Depression - besteht eine genetische Verbindung?: Übersicht und klinischer Fall [PDF]

, 2018
Zusammenfassung: Der Morbus Darier ist eine seltene Hauterkrankung, die autosomal-dominant vererbt wird und durch eine Mutation im SERCA (sarco/endoplasmatic reticulum calcium transporter)-2-Gen verursacht wird.
Bach, D., Moggi, F., Müller, T., Seifritz, E., Strik, W., Wirtz, G.   +5 more
core  

Insulin-like growth factor 2 overexpression induces β-Cell dysfunction and increases beta-cell susceptibility to damage [PDF]

, 2015
The human insulin-like growth factor 2 (IGF2) and insulin genes are located within the same genomic region. Although human genomic studies have demonstrated associations between diabetes and the insulin/IGF2 locus or the IGF2 mRNA-binding protein 2 ...
Agudo, Judith, Bosch i Tubert, Fàtima, Casaña Lorente, Estefania, Casellas, Alba, Garcia Martínez, Miquel, Haurigot Mendonça, Virginia, Jiménez Cenzano, Verónica, Mallol Dominguez, Cristina, Mercè Obach, Mercè, Molas, Maria, Morró Larrubia, Meritxell, Ricardo Lage, Ruberte París, Jesús, Salavert, Ariana, Vilà Prats, Laia   +14 more
core   +2 more sources

Low‐dose lithium supplementation promotes musculoskeletal and metabolic health in ovariectomized female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Low‐dose lithium supplementation in ovariectomized mice enhances skeletal muscle contractility (isometric force and fatigue resistance), SERCA function and promotes favourable transcriptional reprogramming, while increasing bone density and modestly improving insulin sensitivity.
Bianca M. Marcella, Jessica L. Braun, Amélie A.T. Marais, Briana L. Hockey, Mia S. Geromella, Ryan W. Baranowski, Rene Vandenboom, Rebecca E.K. MacPherson, Val A. Fajardo   +8 more
wiley   +1 more source

Darier’s Disease: Report of a Case with Facial Involvement

Case Reports in Dermatology, 2019
Darier’s disease is a relatively rare autosomal dominant genodermatosis with a defect in the desmosomal attachment due to a mutation in the ATP2A2 gene.
Chaninan Kositkuljorn, Poonkiat Suchonwanit   +1 more
doaj   +1 more source

Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic agent trastuzumab [PDF]

, 2012
Trastuzumab (TZM), a monoclonal antibody against the ERBB2 protein, increases survival in ERBB2-positive breast cancer patients. Its clinical use, however, is limited by cardiotoxicity. We sought to evaluate whether TZM cardiotoxicity involves inhibition
A. c. Wolff, A. s. Barth, A. s. Ho, B. O'Rourke, CHIMENTI, ISOTTA, D. r. Davis, E. Kizana, E. Marban, G. Gerstenblith, I. Terrovitis, R. r. Smith, T. s. Li, Y. Zhang   +12 more
core   +1 more source

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

Veterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie, Jason B. Pieper, Darren J. Berger   +2 more
wiley   +1 more source

Guttate hypopigmentation in Darier disease: A rare presentation

Pigment International
Darier disease (DD) is an autosomal dominant genodermatosis attributed to ATP2A2 gene mutation which encodes the sarco/endoplasmic reticulum Ca2+ATPase isoform 2.
Aradhana Rout, Ashish Kumar Pandey, Karthi Kishore   +2 more
doaj   +1 more source

Large autosomal copy-number differences within unselected monozygotic twin pairs are rare [PDF]

, 2015
Monozygotic (MZ) twins form an important system for the study of biological plasticity in humans. While MZ twins are generally considered to be genetically identical, a number of studies have emerged that have demonstrated copy-number differences within ...
Martin, Nicholas G., Mcrae, Allan F., Montgomery, Grant W., Visscher, Peter M.   +3 more
core   +2 more sources