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Moderate maternal nutrient restriction alters type II alveolar epithelial cell density in the non‐human primate fetal lung

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2713-2728, 1 May 2026.
Abstract Restriction of fetal substrate supply has an adverse effect on surfactant maturation in the lung and thus affects the transition from in utero placental oxygenation to pulmonary ventilation ex utero. However, the consequences of reduced fetal substrate supply are dependent on the timing of gestation, severity and duration.
Mitchell C. Lock   +5 more
wiley   +1 more source
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CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function

Biochemical Pharmacology, 2014
The overexpression of ATP-binding cassette (ABC) transporters often leads to the development of multidrug resistance (MDR), which is the major factor contributing to the failure of chemotherapy. The objective of this study was to investigate the enhancement of CEP-33779, a small-molecule inhibitor of Janus kinase 2 (JAK2), on the efficacy of ...
Shang-jun, Tang   +10 more
openaire   +2 more sources

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