Results 181 to 190 of about 29,024 (195)

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

From metabolic alterations to chronic inflammation: mechanisms and immunoregulation of metabolic reprogramming in COPD. [PDF]

Front Immunol
Zeng S, Zhang Y, Li S, Li Z, Li P, Xie J, Zhang J, Xie L, Yang Y.   +8 more
europepmc   +1 more source

Bioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal Tissues

Advanced Science, EarlyView.
This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo, Gabriela S. Kronemberger, Daniel J. Kelly   +2 more
wiley   +1 more source

The metabolic intersection between immunosenescence and neuroinflammation in amyotrophic lateral sclerosis. [PDF]

J Inflamm (Lond)
Tsang VSK, Malaspina A, Henson SM.
europepmc   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source

Metabolic toxicity and neurological dysfunction in methylmalonic acidemia: from mechanisms to therapeutics. [PDF]

Mol Med
Du M, Li M, Wu S, Wu X, Chen Y, Zhu C.
europepmc   +1 more source

Structural studies on dehydrogenases [PDF]

, 2014
Elbrghathi, Abdelhamid
core  

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

PINK1/Parkin promotes liver regeneration via Sigma-1 ubiquitination to inhibit ER-Mitochondrial calcium transfer. [PDF]

Theranostics
Xu J, Wang Y, Zhong W, Hu H, Zhang Y, Gao Y, Wang P, Rao Z, Zhou H, Wang X.   +9 more
europepmc   +1 more source

Effects of nicorandil on inflammatory response, oxidative stress and myocardial fibrosis after myocardial infarction. [PDF]

BMC Cardiovasc Disord
Peng J, Hu L, Xiao P, Xiang T, Huang M, Li R, Lei J, Yang Z, Dai X.   +8 more
europepmc   +1 more source