Results 41 to 50 of about 29,024 (195)

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

open access: yesArthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla   +13 more
wiley   +1 more source

Comprehensive analysis of metabolic pathways through the combined use of multiple isotopic tracers [PDF]

open access: yes, 2006
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2006.Includes bibliographical references (p. 287-294).Metabolic Flux Analysis (MFA) has emerged as a tool of great significance for metabolic engineering and the ...
Antoniewicz, Maciek Robert
core  

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

The Structural and Functional Roles of Critical Amino Acid Residues in Drosophila Alcohol Dehydrogenase. [PDF]

open access: yes, 1989
Alcohol dehydrogenase (ADH, alcohol:NAD oxidoreductase, EC1.1.1.1) from Drosophila melanogaster (DmADH) is unique among alcohol dehydrogenases in metal ion requirement, substrate preference, and stereospecificity of hydride transfer.
Chen, Zhuo
core   +2 more sources

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

open access: yesAdvanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida   +16 more
wiley   +1 more source

The role of vacuolar H+-ATPase in exocytic and endocytic membrane transport processes [PDF]

open access: yes, 1999
The role of vacuolar H⁺-ATPase (V-ATPase) in exocytic and endocytic membrane transport processes was studied by using its specific inhibitor, bafilomycin A1 (Baf A1), as a tool. On the exocytic pathway, both brefeldin A- and nocodazole-induced retrograde
Palokangas, Harri
core  

The identification and analysis of mutation in the Cockayne Syndrome B gene [PDF]

open access: yes, 1999
Cockayne Syndrome (CS) is a rare autosomal recessive disorder characterised by neurodegeneration, dwarfism and at least three of the following; hearing loss, dental caries, pigmentary retinopathy, characteristic facial appearance and photosensitivity ...
Mallery, Donna Louise
core   +1 more source

Reevaluating the Activity of ZIF‐8 Based FeNCs for Electrochemical Ammonia Production

open access: yesAdvanced Functional Materials, EarlyView.
Though receiving much attention, the field of electrochemical nitrogen reduction reaction (eNRR) to ammonia is marked by doubts about whether this reaction is possible in aqueous media. This work sheds light on this question for iron single‐atom on N‐doped carbon (FeNC) catalysts—a class of well‐known catalysts that is also worth testing for the sister
Caroline Schneider   +6 more
wiley   +1 more source

Regulation of the catalytic and allosteric properties of photoreceptor phosphodiesterase (PDE6) by the glutamic acid-rich protein-2 (GARP2) [PDF]

open access: yes, 2013
The photoreceptor phosphodiesterase (PDE6) must be precisely regulated to control the sensitivity, amplitude, and kinetics of the photoresponse during excitation, termination and adaptation to light stimulation in rod and cone photoreceptors. The central
Yao, Wei
core   +2 more sources

Defects Dynamic in Photo‐Excited CeO2 and their Influence on CO2 Photoreduction

open access: yesAdvanced Functional Materials, EarlyView.
X‐ray photoelectron spectroscopy study under light excitation is presented to track the defect dynamic (Ce4+ to Ce3+) in CeO2. Surface enhanced Raman spectroscopy confirmed the key role of Ce3+ states in controlling charge and energy transfer across the CeO2‐dye molecule interface.
Rambabu Yalavarthi   +3 more
wiley   +1 more source

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