Bis(benzofuran-thiazolidinone)s and bis(benzofuran-thiazinanone)s as inhibiting agents for chikungunya virus [PDF]
Molecular basis of virus replication, viral pathogenesis and antiviral ...
Albulescu, I.C.+6 more
core +2 more sources
Addition of terlipressin to initial volume resuscitation in a pediatric model of hemorrhagic shock improves hemodynamics and cerebral perfusion [PDF]
Hemorrhagic shock is one of the leading causes of mortality and morbidity in pediatric trauma. Current treatment based on volume resuscitation is associated to adverse effects, and it has been proposed that vasopressors may be used in the pharmacological
Galbarriatu, Lara+8 more
core +1 more source
Cerebral autoregulation and cerebral blood flow response to mean arterial pressure challenge following induction of general anaesthesia for neuroradiology procedure [PDF]
IntroductionIntraoperative hypotension is common following general anaesthesia induction with propofol, but its impact on cerebral autoregulation (CA) remains unclear.
Elsa Manquat+12 more
core +1 more source
Effect of nitrous oxide on cisatracurium infusion demands: a randomized controlled trial [PDF]
Background Recent studies have questioned our previous understanding on the effect of nitrous oxide on muscle relaxants, since nitrous oxide has been shown to potentiate the action of bolus doses of mivacurium, rocuronium and vecuronium.
AF Kopman+22 more
core +3 more sources
Postoperative Cardiac Complications in Patients Undergoing Laryngectomies [PDF]
Introduction: The European Society of Cardiology provides guidelines for preoperative cardiac risk assessment in patients undergoing laryngectomies. Cardiovascular risk factors: chronic congestive heart failure, ischemic heart disease, severe arrhythmias,
Belitova, M.+4 more
core +2 more sources
Alpha rhythm collapse predicts iso-electric suppressions during anesthesia. [PDF]
Could an overly deep sedation be anticipated from ElectroEncephaloGram (EEG) patterns? We report here motifs hidden in the EEG signal that predict the appearance of Iso-Electric Suppressions (IES), observed during epileptic encephalopathies, drug ...
Cartailler, Jérôme+4 more
core +1 more source
Serum heparan sulfate levels are elevated in endotoxemia [PDF]
Background Increased vascular permeability is a characteristic feature of sepsis which, in the past, has been ascribed exclusively to a malfunction of endothelial cells.
Chappell, D+8 more
core +3 more sources
State-of-the-art and recent developments of immobilized polysaccharide-based chiral stationary phases for enantioseparations by high-performance liquid chromatography (2013–2017) [PDF]
Polysaccharide-based chiral stationary phases have been recognized as one of the most powerful ones for high performance liquid chromatography (HPLC) separations of chiral compounds in analytical and also in preparative scale.
Keunchkarian, Sonia, Padró, Juan Manuel
core +4 more sources
ABSTRACT Background Neuromuscular blocking agents (NMBAs) are a crucial component of anesthesia and intensive care through the relaxation of skeletal muscles. They can lead to adverse reactions such as postoperative residual neuromuscular block. Only one agent is capable of an instant block reversal in deep block situations, but is restricted to ...
Hélène Letscher+6 more
wiley +1 more source
Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs [PDF]
Mood disorders (depression, bipolar disorders) are prevalent and disabling. They are also highly co-morbid with other psychiatric disorders. Currently there are no objective measures, such as blood tests, used in clinical practice, and available ...
Bhairo, S.+12 more
core +1 more source