Results 11 to 20 of about 111,824 (315)
Nature Reviews Disease PrimersBiliary atresia (BA) is a progressive inflammatory fibrosclerosing disease of the biliary system and a major cause of neonatal cholestasis. It affects 1:5,000-20,000 live births, with the highest incidence in Asia. The pathogenesis is still unknown, but emerging research suggests a role for ciliary dysfunction, redox stress and hypoxia.
Paul K. H. Tam +9 more
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Colonic Atresia Associated with Biliary Atresia
Journal of Indian Association of Pediatric Surgeons, 2023 Colonic atresia (CA) is an uncommon type of intestinal atresia commonly associated with other anomalies, while biliary atresia (BA) is also rare but usually an isolated anomaly. The pathogenesis for either of the anomalies is unclear. The co-occurrence of both pathologies has not been mentioned in the literature.
Shailesh Solanki +3 more
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Biliary Atresia in Children: Update on disease mechanism, therapies, and patient outcomes
Clinical Liver Disease, 2022 Biliary atresia is a rare disease but remains the most common indication for pediatric liver transplantation as there are no effective medical therapies to slow progression after diagnosis.
Swati Antala, Sarah A. Taylor
semanticscholar +1 more source
Biliary Atresia – emerging diagnostic and therapy opportunities
EBioMedicine, 2021 Biliary Atresia is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. In this review, we describe recent progress in the understanding of liver development with a focus on cholangiocyte differentiation and how use of technical ...
U. Lendahl, V. Lui, P. Chung, P. Tam
semanticscholar +1 more source
Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia
Hepatology, 2021 Biliary atresia is a severe inflammatory and fibrosing cholangiopathy of neonates of unknown etiology. The onset of cholestasis at birth implies a prenatal onset of liver dysfunction.
S. Amarachintha +8 more
semanticscholar +1 more source
Atresia of ovarian follicles in fishes, and implications and uses in aquaculture and fisheries
Journal of Fish Diseases, 2021 Atresia of ovarian follicles, that is the degenerative process of germ cells and their associated somatic cells, is a complex process involving apoptosis, autophagy and heterophagy.
A. Corriero +3 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2020 Importance Treating biliary atresia in newborns earlier can delay or prevent the need for liver transplant; however, treatment typically occurs later because biliary atresia is difficult to detect during its early stages.
S. Harpavat +9 more
semanticscholar +1 more source
Journal of Indian Association of Pediatric Surgeons, 2008 Biliary atresia (BA) is a cholangiodestructive disease affecting biliary tract, which ultimately leads to cirrhosis, liver failure and death if not treated. The incidence is higher in Asian countries than in Europe. Up to 10% of cases have other congenital anomalies, such as polysplenia, asplenia, situs inversus, absence of inferior vena cava and pre ...
Sinha, C.K., Davenport, Mark
openaire +3 more sources
Biliary atresia: pathology, etiology and pathogenesis
Future Science OA, 2020 Biliary atresia is a progressive fibrosing obstructive cholangiopathy of the intrahepatic and extrahepatic biliary system, resulting in obstruction of bile flow and neonatal jaundice.
M. Vij, M. Rela
semanticscholar +1 more source
Audiology Research, 2023 This systematic review evaluates the efficacy and benefit of cartilage conduction hearing aids (CC-HAs) and that factors that influence purchasing decisions. The hearing thresholds and functional gain following CC-HA wear were synthesised.
Bei Li +6 more
doaj +1 more source