Results 221 to 230 of about 111,824 (315)

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Subtle Presentation of Type B Esophageal Atresia. [PDF]

Cureus
Fortich S, Mobli K, Ewing E, Radhakrishnan R.   +3 more
europepmc   +1 more source

Transcranial Doppler Ultrasound Velocity Measurements in Children With Sickle Cell Disease in Kenya

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell disease (SCD) is the most common inherited haemoglobinopathy and poses a high public health burden in Sub‐Saharan Africa. Children with sickle cell anaemia are at a highrisk of ischemic stroke, and transcranial Doppler (TCD) ultrasonography helps identify those at highest risk for primary stroke prevention.
Catherine Mwalimu, Oscar Odhiambo, Elaine Mashisia, Teresa Mwanja, Allan Ade, Maria Vittoria De Vita, Katherine Oyieke, Pauline Samia, Fenella Kirkham, Samson Gwer   +9 more
wiley   +1 more source

Differentiation of biliary atresia using a rapid point-of-care matrix metalloproteinase-7 assay: A multicenter diagnostic study. [PDF]

Hepatol Commun
Chi S, Huang J, Yu P, Niu H, Zheng Z, Zhou Y, Sun D, Cai C, Hua J, Chen P, Zhang M, Zhang X, Cao G, Li S, Rong L, Chen Y, Tam PK, Tang ST.   +17 more
europepmc   +1 more source

Neurodevelopmental assessment at 24 months in infants with esophageal atresia: A prospective cohort study

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1386-1393, June 2026.
Abstract Objective To evaluate neurodevelopment at 24 months in infants surgically treated for esophageal atresia (EA), using the ages and stages questionnaire (ASQ), and identify perinatal and early‐life factors associated with developmental delay. Methods Infants with EA were prospectively enrolled in a structured multidisciplinary follow‐up program.
Julia Tagmouti, Manon Midavaine, Victor Sartorius, Nicolas Vinit, Elise Leroy‐Terquem, Sylvie Beaudoin, Elsa Kermorvant‐Duchemin, Véronique Rousseau, Alexandre Lapillonne   +8 more
wiley   +1 more source

Analysis of Prevalence and Mortality Among Neonates and Children With Intestinal Atresia: A Multinational Study, 1974-2015. [PDF]

Birth Defects Res
Carreño A, Aguilera MP, Ibañez L, Sarmiento K, Gili JA, Siffel C, Nembhard WN, Bergman JEH, Bermejo-Sánchez E, Tagliabue G, Dastgiri S, Feldkamp ML, Pocius S, Gatt M, Martínez L, Canessa MA, Groisman B, Källén K, Landau D, Lelong N, Morgan M, Arteaga-Vázquez J, Santoroi M, Rissmann A, Sipek A, Szabova E, Wertelecki W, Canfield MA, Mastroiacovo P, Zarante I.   +29 more
europepmc   +1 more source

Retrospective chart review of immobilized lipase cartridge use in children with short bowel syndrome

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1488-1494, June 2026.
Abstract This retrospective, single‐center chart review studied the use of an in‐line, immobilized lipase cartridge (ILC) in children with short bowel syndrome (SBS) at Children's Mercy Hospital. For parenteral nutrition (PN)‐dependent patients, the primary endpoint was enteral feeding progression, evaluated by comparing monthly change from baseline in
Elizaveta Khenner, Jennifer L. Morton, Laura Green, Ashlee Yoder, Kayla Paul, Ann E. Remmers, William O. San Pablo   +6 more
wiley   +1 more source

Non-visualization of the fetal gallbladder with ultrasound in the second trimester in a Chinese cohort: prognosis and clinical consultation. [PDF]

BMC Pregnancy Childbirth
Ding H, Wang Y, He F, Wang Y, Zeng K, Zhang Z, Li J, Chen L.   +7 more
europepmc   +1 more source

CUL3‐Related Neurodevelopmental Disorder: Expanding the Prenatal Phenotype

Prenatal Diagnosis, Volume 46, Issue 7, Page 1122-1129, June 2026.
ABSTRACT Objective Pathogenic variants of the CUL3 gene are known to cause a neurodevelopmental disorder with a partially described prenatal phenotype. This study further characterizes and expands the spectrum of prenatal sonographic findings associated with the disorder to improve prenatal diagnosis and counseling.
Yoel Gofin, Tania Dery, Tamar Tenne, Racheli Goldfarb Yaacobi, Emilie Block, Marina Lifshitc Kalis, Hagar Mor‐Shaked, Liza Douiev‐Charpak, Rivka Birnbaum, Mordechai Shohat, Ofer Markovich, Debora Kidron, Rivka Sukenik‐Halevy   +12 more
wiley   +1 more source

Upregulated beta-defensin-1 in murine and human biliary atresia associates with human native liver survival. [PDF]

Sci Rep
Slavetinsky C, Basenach J, Damm P, Bertolini C, Holweg M, Hartleif S, Hilberath J, Singer S, Petersen C, Fuchs J, Sturm E.   +10 more
europepmc   +1 more source