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Biliary atresia (BA) is a progressive inflammatory fibrosclerosing disease of the biliary system and a major cause of neonatal cholestasis. It affects 1:5,000-20,000 live births, with the highest incidence in Asia. The pathogenesis is still unknown, but emerging research suggests a role for ciliary dysfunction, redox stress and hypoxia.
Paul Kwong-Hang Tam +2 more
exaly +4 more sources
This PrimeView highlights oesophageal atresia, a congenital abnormality of the oesophagus that requires surgical reconstruction soon after birth.
, Maartje Singendonk, Luigi Dall'oglio
exaly +7 more sources
Biliary Atresia: Clinical and Research Challenges for the Twenty‐First Century
Biliary atresia (BA) is a fibroinflammatory disease of the intrahepatic and extrahepatic biliary tree. Surgical hepatic portoenterostomy (HPE) may restore bile drainage, but progression of the intrahepatic disease results in complications of portal ...
Jorge A Bezerra +2 more
exaly +2 more sources
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia
Chatmanee Lertudomphonwanit +2 more
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Oesophageal atresia associated with pyloric atresia [PDF]
Pyloroduodenal atresia is a rare and usually isolated anomaly. Crowe and Sumner (1978) recently reported a newborn with pyloroduodenal atresia, isolated oesophageal atresia (Gross Type 1) and cardiac and skeletal malformations. We wish to report a similar case and review the diagnostic techniques that can lead to the correct diagnosis of a second ...
Jack O. Haller +3 more
openaire +2 more sources
Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes
Akihiro Asai +2 more
exaly +2 more sources
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Biliary atresia: A comprehensive review
Journal of Autoimmunity, 2016Mark Davenport
exaly +2 more sources

