Results 91 to 100 of about 405,391 (337)

Severe Nerve Enlargement in SOS2‐Related Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan syndrome is a genetic multisystem congenital disorder, caused by pathogenic variants in genes that encode components of the RAS/MAPK signaling pathway. Pathogenic variants in SOS2 represent less than 2% of cases with NS. The phenotype includes a particularly high prevalence (65%) of lymphatic disease. Recently, severe nerve enlargements
Erika Leenders, Fieke Draaisma, Corrie E. Erasmus, Catelijne Coppens, Lotte E. R. Kleimeier, Melanie Burgers, Tuula Rinne, Martin Zenker, Laura Mazzanti, Wesley Reintjes, Nens van Alfen, Jos M. T. Draaisma   +11 more
wiley   +1 more source

Feasibility of Left Atrial Appendage Occlusion in Left Atrial Appendage Thrombus

JACC: Clinical Electrophysiology, 2020
This study aimed to investigate the feasibility and safety of left atrial appendage occlusion (LAAO) procedures in patients with persistent left atrial appendage (LAA) thrombus.The left atrial appendage (LAA) is the most common site of thrombus formation in patients with nonvalvular atrial fibrillation (AF).
Sharma S. P., Cheng J., Turagam M. K., Gopinathannair R., Horton R., Lam Y. -Y., Tarantini G., D'Amico G., Freixa Rofastes X., Lange M., Natale A., Lakkireddy D. R.   +11 more
openaire   +3 more sources

Left atrial appendage function evaluated by transesophageal echocardiography in patients with atrial fibrillation.

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011
Recurrences of atrial fibrillation in patients with embolic events lead the study of the left atrial appendage, where 90% of thrombus arelodged.To evaluate the function of the left atrial appendage in patients with atrial fibrillation.An observational ...
Raymid García Fernández, Juan Valiente Mustelier, Biolkis Sorio Valdés, Raúl Díaz Padrón Camejo, Teddy O. Tamargo Barbeito, Edsel Gutiérrez Chiguanto, Reinel Álvarez Plasencia   +6 more
doaj  

Device-Assisted Left Atrial Appendage Exclusion: From Basic Sciences to Clinical Applications

Journal of Cardiovascular Development and Disease
Device-assisted left atrial appendage exclusion plays a crucial role in the prevention of fatal ischemic complications in patients with atrial fibrillation and contraindications to anticoagulation treatment. Various devices with different safety profiles
Julia Izabela Karpierz, Michał Piotrowski, Krzysztof Bartuś, Radosław Chmiel, Katarzyna Wijatkowska, Artur Słomka   +5 more
doaj   +1 more source

Evaluating Real-World Clinical Outcomes in Atrial Fibrillation Patients Receiving the WATCHMAN Left Atrial Appendage Closure Technology: Final 2-Year Outcome Data of the EWOLUTION Trial Focusing on History of Stroke and Hemorrhage

Circulation: Arrhythmia and Electrophysiology, 2019
Background: Left atrial appendage occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials.
L. Boersma, H. Ince, S. Kische, E. Pokushalov, T. Schmitz, B. Schmidt, T. Gori, F. Meincke, A. Protopopov, T. Betts, P. Mazzone, D. Foley, M. Grygier, H. Sievert, T. D. De Potter, E. Vireca, K. Stein, M. Bergmann, A. Al Nooryani, T. Fiedler, G. Senatore, F. Brigadeau, P. Defaye, E. Teiger, J. Bonnet, C. Wald, T. Szili-Torok, W. Tschishow, D. Crossland, A. Vahanian, I. Cruz-González, J. Thambo, Faisal Al Smadi, H. Mudra, Robin Molitoris, R. Folkeringa, Y. Stevenhagen, D. Gras, C. Tamburino, G. Molon, M. Spence, Eduardo Infante Oliveira, E. Merkulov, A. Sukiennik, T. Wong, M. Busch, L. Boldt, G. Nickenig, M. Neef   +48 more
semanticscholar   +1 more source

Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal [PDF]

, 2017
Current guidelines support the well-established clinical practice that patients who present with atrial fibrillation (AF) of less than 48 hours duration should be considered for cardioversion, even in the absence of pre-existing anticoagulation. However,
Rankin, Alastair J., Rankin, Stephen H.
core   +1 more source

An optimized perfusate for enhanced rat ex vivo lung perfusion and lung transplant models

Animal Models and Experimental Medicine, EarlyView.
We explored a low‐cost and efficient perfusate composition for use in rat ex vivo lung perfusion (EVLP) and lung transplant models. This perfusate demonstrates better biocompatibility, likely due to a reduction in immune responses associated with high doses of xenogenic proteins, resulting in less lung injury posttransplantation.
Jie Zhang, Xuanlin Zhang, Jianxing He
wiley   +1 more source

Left Atrial Appendage Occlusion Guided Only by Transesophageal Echocardiography

Cardiology Research and Practice, 2019
Aims. To investigate a new method of left atrial appendage occlusion without fluoroscopy. Methods and Results. We performed left atrial appendage occlusion for 14 patients with atrial fibrillation in our hospital. All of the surgeries were completed in a
Jinlong Zhao, Feng Li, Yueli Zhang, Zhongyun Zhuang, Man Wang, Liang Fu, Yinkai Ni, Zhexin Lu, Zonghui Chen, Cheng Zhang   +9 more
doaj   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +15 more
wiley   +1 more source

Epicardial delivery of autologous atrial appendage micrografts during coronary artery bypass surgery—safety and feasibility study

Pilot and Feasibility Studies, 2017
Background The atrial appendages are a tissue reservoir for cardiac stem cells. During on-pump coronary artery bypass graft (CABG) surgery, part of the right atrial appendage can be excised upon insertion of the right atrial cannula of the heart-lung ...
Annu Nummi, Tuomo Nieminen, Tommi Pätilä, Milla Lampinen, Miia L. Lehtinen, Sari Kivistö, Miia Holmström, Erika Wilkman, Kari Teittinen, Mika Laine, Juha Sinisalo, Markku Kupari, Esko Kankuri, Tatu Juvonen, Antti Vento, Raili Suojaranta, Ari Harjula, The AADC consortium   +17 more
doaj   +1 more source