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Atrial fibrosis progression in patients with no history of atrial fibrillation

Journal of Cardiovascular Electrophysiology, 2021
AbstractBackgroundUnexpected high levels of atrial fibrosis are found in individuals with no history of atrial fibrillation (AF). The temporal behavior of atrial fibrosis in this population is still unknown. We sought to investigate the progression and predictors of atrial fibrosis in non‐AF individuals.MethodsNon‐AF individuals at baseline who ...
Lilas Dagher   +8 more
openaire   +2 more sources

Assessment of atrial fibrosis for the rhythm control of atrial fibrillation [PDF]

open access: yesInternational Journal of Cardiology, 2016
Rhythm control of atrial fibrillation (AF) remains challenging, with modest long-term success rates. Atrial fibrosis has been associated with AF, but the clinical utility of assessment of this fibrosis has yet to be fully elucidated. In this paper we review the current state of understanding of the pathophysiology of atrial fibrosis in AF, and its ...
Gordon A Begg   +2 more
exaly   +3 more sources

Atrial fibrosis: a risk stratifier for atrial fibrillation

Expert Review of Cardiovascular Therapy, 2013
Atrial fibrillation (AF), especially persistent and long-standing persistent AF, may result in electro-anatomical changes in the left atrium, resulting in remodeling and deposition of fibrous tissue. There are emerging data that atrial substrate modification may increase the risk of thromboembolic complications, including stroke.
Poonam, Velagapudi   +3 more
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Atrial Arrhythmias in Endomyocardial Fibrosis

Cardiology, 1972
Atrial arrhythmias occurred in 34 out of 97 patients with endomyocardial fibrosis. In 21 instances, atrial fibrillation or flutter was persistent. In 13 cases, atrial arrhythmia was transient and intermittent. It was necessary, in some patients with rapid ventricular re sponses, to employ direct-current cardioversion.
K, Somers   +3 more
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An Atrial fibrosis-based Approach for Atrial Fibrillation Ablation

Future Cardiology, 2015
Since the emergence of atrial fibrillation (AF) ablation as a reliable method of restoring sinus rhythm, various approaches have been used to improve the efficacy while maximizing the safety of ablation. A major hurdle to optimizing outcomes for AF ablation has been the failure to recognize that the substrate of the individual patient plays a ...
Frederick T, Han, Nassir, Marrouche
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EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation

Journal of Molecular and Cellular Cardiology, 2019
Angiotensin II (Ang-II)-induced fibroblast differentiation plays an important role in the development of atrial fibrosis and atrial fibrillation (AF). Here, we show that the expression of the histone methyltransferase enhancer of zeste homolog 2 (EZH2) is increased in atrial muscle and atrial fibroblasts in patients with AF, accompanied by significant ...
Bin-Feng Mo, Long Chen, Guojian Fang
exaly   +3 more sources

Left Atrial Fibrosis and Recurrent Arrhythmia

JAMA, 2014
In the Delayed-Enhancement MRI Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation (DECAAF) study, Dr Marrouche and colleagues1 demonstrated that assessment of left atrial fibrosis with delayed enhancement magnetic resonance imaging (MRI) was associated with the likelihood of recurrent arrhythmia after catheter ablation ...
Tops, L.F., Schalij, M.J.
openaire   +3 more sources

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