Results 211 to 220 of about 19,328,196 (346)

Residual Shunt at 6 Months Follow‐up After Percutaneous Patent Foramen Ovale Closure in CAHAL: A Comparison of Occlutech and Amplatzer

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Residual shunt is a known complication in percutaneous patent foramen ovale (PFO) closure, and moderate to large residual shunt has been associated with an increased risk of recurrent stroke. Device‐related factors, such as device size, have been associated with residual shunt, but comparative data per device type are scarce.
Jelle D. Nieuwendijk   +12 more
wiley   +1 more source

Long‐Term Prognostic Value of Angiography‐Derived Quantitative Flow Ratio and Radial Wall Strain in Untreated Intermediate Coronary Stenoses: A Retrospective Cohort Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Quantitative flow ratio (QFR) measures angiography‐derived coronary physiology, whereas radial wall strain (RWS) characterizes cyclic lumen deformation. We investigated their complementary long‐term prognostic information in untreated intermediate coronary stenoses and assessed the internal validity of their combined prediction ...
Yixing Chen   +9 more
wiley   +1 more source

Assembly and Maintenance of Myofibrils in the Heart

open access: yesCytoskeleton, EarlyView.
ABSTRACT The assembly of actin and myosin to the paracrystalline arrangement of myofibrils in striated muscle, that is, heart and skeletal, has puzzled many a cell biologist. Different models, based on cultured cardiomyocytes, were proposed for the last 30 years to explain the sequence of events.
Elisabeth Ehler
wiley   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul   +5 more
wiley   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

Prognostic implications of impaired three-dimensional left atrial function and stiffness in primary mitral regurgitation. [PDF]

open access: yesCardiovasc Ultrasound
Berg-Hansen CE   +6 more
europepmc   +1 more source

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

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