Results 71 to 80 of about 136,303 (402)

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M., Cantin, M., Gerbes, Alexander L., Paumgartner, Gustav, Thibault, G., Vollmar, Angelika M.   +5 more
core   +1 more source

Cyclic guanosine monophosphate mediates vascular relaxation induced by atrial natriuretic factor.

HYPERTENSION, 1985
The biochemical mechanism of action of synthetic atrial natriuretic factor (atriopeptin II) was studied in vascular smooth muscle of the rabbit thoracic aorta.
E. Ohlstein, B. Berkowitz
semanticscholar   +1 more source

Increased Thrombogenicity is Associated With Coronary Microvascular Dysfunction in Patients With STEMI—A Proof‐of‐Concept Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Up to 50% of patients with ST‐segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) develop coronary microvascular dysfunction (CMD). Aims This study aims to assess whether a prothrombotic state of coronary blood, defined by thromboelastography (TEG), is associated with post ...
Roberto Scarsini, Denis Leonardi, Andrea Bottardi, Concetta Mammone, Leonardo Portolan, Caterina Butturini, Verdiana Galli, Francesco Della Mora, Alessandro Ruzzarin, Sara Pazzi, Anna Piccoli, Simone Fezzi, Domenico Tavella, Gabriele Pesarini, Leonardo Gottin, Flavio Ribichini   +15 more
wiley   +1 more source

Model for predicting the recurrence of atrial fibrillation after monopolar or bipolar radiofrequency ablation in patients with AF and mitral valve disease

Journal of Cardiothoracic Surgery
Objectives This study aimed to identify the risk factors for postoperative atrial fibrillation in patients with valvular atrial fibrillation, and establish predictive models of atrial fibrillation recurrence.
Wei Si, Peng Teng, Liang Ma
doaj   +1 more source

Balloon‐Expandable Versus Self‐Expanding Valves in Bicuspid Aortic Stenosis: Insights From the SWEDEHEART Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter aortic valve replacement (TAVR) is increasingly used in patients with bicuspid aortic valve (BAV) stenosis, but there is limited comparative data on balloon‐expandable (BEV) versus self‐expanding valves (SEV) in this population. Aim To compare clinical and hemodynamic outcomes between BEVs and SEVs in patients with BAV
Antros Louca, Joakim Sundström, Araz Rawshani, Henrik Hagström, Magnus Settergren, Stefan James, Sasha Koul, Kristofer Skoglund, Dan Ioanes, Sebastian Völz, Anna Myredal, Oskar Angerås, Petur Petursson, Truls Råmunddal   +13 more
wiley   +1 more source

Effect of hypotensive hypovolemia and thoracic epidural anesthesia on plasma pro-atrial natriuretic peptide to indicate deviations in central blood volume in pigs: a blinded, randomized controlled trial

Local and Regional Anesthesia, 2019
Rune B Strandby,1 Rikard Ambrus,1 Michael P Achiam,1 Amalie Henriksen,1 Jens P Goetze,2 Niels H Secher,3 Lars B Svendsen11Department of Surgical Gastroenterology; 2Department of Clinical Biochemistry; 3Department of Anesthesiology, Rigshospitalet ...
Strandby RB, Ambrus R, Achiam MP, Henriksen A, Goetze JP, Secher NH, Svendsen LB   +6 more
doaj  

Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cardiovascular functions. Krüppel‐like factor 5 (KLF5) exerts diverse functions in the cardiovascular system.
Guoliang Meng, Yujiao Xiao, Yan Ma, Xin Tang, Liping Xie, Jieqiong Liu, Yue Gu, Ying Yu, Chung‐Min Park, Ming Xian, Xin Wang, Albert Ferro, Rui Wang, Philip K. Moore, Zhiren Zhang, Hong Wang, Yi Han, Yong Ji   +17 more
doaj   +1 more source

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source

Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma

Respiratory Research, 2009
Background Atrial natriuretic peptide (ANP) and its receptor, NPRA, have been extensively studied in terms of cardiovascular effects. We have found that the ANP-NPRA signaling pathway is also involved in airway allergic inflammation and asthma.
Cormier Stephania A, Giaimo Joseph D, Ahlert Terry A, Hellermann Gary, Chen Dongqing, Kong Xiaoyuan, Xu Weidong, Wang Xiaoqin, Li Xu, Lockey Richard F, Mohapatra Subhra, Mohapatra Shyam S   +11 more
doaj   +1 more source