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Atrial natriuretic peptide in human hypertension
European Heart Journal, 1987Preliminary reports are that plasma levels of immunoreactive atrial natriuretic peptide (IR-ANP) are higher in essential hypertensive patients than in normotensive controls, and that the urinary response to injected alpha human atrial natriuretic peptide (alpha-hANP) is augmented in essential hypertension.
Ian Crozier +4 more
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Atrial Natriuretic Peptide and Atrial Size
1989Enlarged plasma volume causes an increase of atrial size, and leads to a higher wall tension playing an important role in the secretion of ANP. Dependent on the compliance of the atrial myocardium different pressures may occur. Therefore it is likely that an atrial dilation — but not necessarily the increase of the atrial pressure — resulted in an ...
M. Krieg +6 more
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Degradation of atrial natriuretic peptide in dogs
Acta Endocrinologica, 1989Abstract. To clarify the degradation of atrial natriuretic peptide (ANP) in dogs, plasma ANP concentrations in blood samples drawn from the coronary sinus, and in simultaneously collected blood samples of the arteries and veins of the lung, liver, kidney, spleen and cervix, and of the supramesenteric artery and the portal vein, were measured, both when
Takashi Masuda +2 more
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Atrial Natriuretic Peptide and Renal Disease
Nephrology Dialysis Transplantation, 1989The discovery by De Bold et al. [1] that the cardiac atria contained a natriuretic substance has led to an explosion of information about atrial natriuretic peptide (ANP) in normal subjects and healthy animals [1-32]. However, it is only in the last few years that attention has focused on ANP in renal disorders, and this article aims to review this ...
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The Biochemistry of Atrial Natriuretic Peptides
1997It is now some 15 yr since de Bold and Sonnenberg and colleagues discovered that the injection of atrial extracts into rats gave rise to a profound diuresis, natriuresis, and hypotension (1). Within a very short time following this discovery it was shown that the agent responsible for this effect was a 28-amino acid, disulfide-bonded peptide that was ...
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Radioimmunoassay of Atrial Natriuretic Peptide
1991Publisher Summary This chapter describes radioimmunoassay (RIA) of atrial natriuretic peptide (APN). Extracts of atrial tissue have been shown to exert a potent natriuretic and diuretic effect activity. The main difference between atrial and ventricular cardiocytes is the presence in the former of specific granules with morphological characteristic ...
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Atrial natriuretic peptide in AMI
American Heart Journal, 1988Bernd Puschendorf +4 more
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Natriuretic peptides and incident atrial fibrillation
American Heart Journal, 2021Claes Held +3 more
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