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Are the atrial peptides a natriuretic hormone?
European Heart Journal, 1987The control of sodium balance plays a vital role in the regulation of both intravascular and extravascular fluid volume. The discovery and synthesis of the atrial natriuretic peptides has led to the suggestion that they may be an important hormone in the control of sodium and water balance.
G. A. Sagnella, G. A. Macgregor
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Atrial natriuretic peptide and oxidative stress
Peptides, 2010Atrial natriuretic peptide (ANP) is a hormone, produced mainly by cardiomyocytes, with a major role in cardiovascular homeostatic mechanisms such as natriuresis and vasodilation, which serve to regulate blood pressure. However, ANP also acts as an autocrine/paracrine factor on other targets such as kidney, lung, thymus, liver and the immune system. ANP
DE VITO, PAOLO+3 more
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Platelet aggregation and atrial natriuretic peptide
General Pharmacology: The Vascular System, 19951. Isolated human platelets were used to investigate the effect of atrial natriuretic peptide (ANP) on in vitro platelet aggregation induced by epinephrine, ADP, collagen and 5-hydroxytryptamine. As a direct stimulant of particulate guanylate cyclase, ANP is known to have no direct effect on platelets which contain soluble guanylate cyclase. 2.
Akgur, S+4 more
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Atrial Natriuretic Peptide in Dumping Syndrome
Digestion, 1993The significance of atrial natriuretic factor (ANF) was investigated in the maintenance of the fluid volume in hypovolemia associated with dumping syndrome following gastric resection. The study was performed on 10 patients with Billroth II procedure. Ten age and sex matched patients--without previous gastric surgery served as controls.
Zsolt Tulassay+3 more
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Atrial natriuretic peptide in hypoxia
Peptides, 2005A growing number of mammalian genes whose expression is inducible by hypoxia have been identified. Among them, atrial natriuretic peptide (ANP) synthesis and secretion is increased during hypoxic exposure and plays an important role in the normal adaptation to hypoxia and in the pathogenesis of cardiopulmonary diseases, including chronic hypoxia ...
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Atrial Natriuretic Peptide in Renal Transplantation [PDF]
Factors related to atrial natriuretic peptide (alpha-ANP) regulation and its potential impact on excretory transplant function were examined in a prospective cohort study of 20 patients with end-stage renal disease over 21 days after allogenic kidney transplantation.
W. Scholtz, J. Plum, B. Grabensee
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The atrial natriuretic peptide: a changing view
Journal of Hypertension, 2001The atrial natriuretic peptide (ANP), a component of the natriuretic peptide family, was discovered in 1981 when de Bold and his coworkers observed a natriuretic effect induced by infusion of atrial extracts in rats. Subsequently, an impressive amount of research has been carried out in order to identify the structure of the active peptide and its ...
RUBATTU, Speranza Donatella+1 more
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Atrial Natriuretic Peptides [PDF]
In 1981 de Bold and colleagues demonstrated that the injection of atrial, but not ventricular, extract into rats caused a natriuresis and diuresis [1]. It is now known that this extract contained a peptide, atrial natriuretic peptide (ANP) or atrial natriuretic factor, which is one of a family of hormones known to have an important role in salt and ...
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Atrial natriuretic peptides and renin release
The American Journal of Medicine, 1988The relationship between endogenous plasma concentrations of atrial natriuretic peptide and renin was examined in resting normal subjects and patients with cardiac impairment. To test the hypothesis that atrial natriuretic peptide inhibits renin secretion, intravenous infusions of atrial natriuretic peptide were administered to normal volunteers ...
A. M. Richards+6 more
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Atrial natriuretic peptide in Cushing’s disease
Journal of Endocrinological Investigation, 1990Atrial Natriuretic Peptide (ANF), is secreted by atrial myocytes in response to atrial stretch. Its plasma levels have been found elevated in conditions leading to salt and fluid repletion and consequent atrial distention. Recently, it has been demonstrated that dexamethasone can enhance ANF secretion, by acting on ANF gene expression and mRNA ...
OPOCHER, GIUSEPPE+7 more
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