Results 291 to 300 of about 68,298 (346)

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 5, Page 1030-1047, March 2026.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero   +11 more
wiley   +1 more source

Molecular Landscape in Limb Anomalies: Diagnostic Yield and New Candidate Genes

open access: yesClinical Genetics, Volume 109, Issue 3, Page 424-436, March 2026.
In 132 individuals with limb anomalies, diagnostic yield was 36% (47/132), including 25 novel variants, three cases with new phenotypes, and two candidate loci, HOXA11 and a small 2q31.1 deletion. Mouse data and exome‐wide analysis, key in identifying the candidate loci, represent an important opportunity for gene discovery.
Akram Mokhtari   +7 more
wiley   +1 more source

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

open access: yesClinical Genetics, Volume 109, Issue 3, Page 529-538, March 2026.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum   +13 more
wiley   +1 more source

Breaking the Barriers: Transseptal Puncture in Patients with Atrial Septal Defect Closure Devices. [PDF]

open access: yesInterv Cardiol
Lo Russo G   +7 more
europepmc   +1 more source

Development of the atrial septum

Heart, 2016
To the Editor, I read with interest the review presented by Asrress et al in your series ‘Education in Heart’.1 I was disappointed to find figure 1 representing a spurious concept of development. Although the concept is to be found in many textbooks of cardiac embryology, it is not necessarily correct.
K N, Asrress   +4 more
openaire   +4 more sources

Inverted Left Atrial Appendage Bonded to Atrial Septum

Canadian Journal of Cardiology, 2013
Inverted left atrial appendage (LAA) is a rare surgical complication. Our patient, a boy aged 2 years, was diagnosed with a partial atrioventricular defect with mild regurgitation of the left atrioventricular valve and a large primum atrial septal defect.
Cláudia Maria Caldas, Moura   +4 more
openaire   +2 more sources

Reliable atrial septostomy by stenting of the atrial septum

Catheterization and Cardiovascular Interventions, 2005
AbstractThe aim of this report was to describe our experience with creating an interatrial communication by stenting the interatrial septum. In many forms of congenital heart disease, the presence of an appropriate interatrial shunt is critical. After the first several weeks of life, balloon atrial septostomy is not effective, and success with other ...
Saar, Danon   +3 more
openaire   +2 more sources

Atrial Tachycardias Originating from the Atrial Septum:

Journal of Cardiovascular Electrophysiology, 2000
Atrial Tachycardia. Introduction: The characteristics of atrial tachycardia (AT) have varied widely among different reports. The anatomic locations of ATs may bias the results. We propose that septal ATs and free‐wall ATs have different characteristics.
C C, Chen   +11 more
openaire   +2 more sources

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