Results 191 to 200 of about 88,913 (308)

Reflex Syncope With Complete Heart Block Triggered by Swallowing in a Patient on Immune Checkpoint Inhibitor Therapy

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon   +3 more
wiley   +1 more source

The Not-So-Fast Tachycardia: A Paradoxical Rhythm Leading to Cardiomyopathy. [PDF]

open access: yesJACC Case Rep
Alnazeer M   +4 more
europepmc   +1 more source

Cerebrovascular regulation during heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Cardioneuroablation Restoring Atrioventricular Conduction in Brugada Syndrome: A Device-Free Approach. [PDF]

open access: yesJACC Case Rep
Chipa-Ccasani F   +9 more
europepmc   +1 more source

Regeneration of the lizard heart after cryoinjury

open access: yesExperimental Physiology, EarlyView.
Abstract Lizards are renowned for their tremendous potential to heal tissues and organs after injury, but little is known about myocardial regeneration in reptiles generally. Here, we study cardiac regeneration in the leopard gecko (Eublepharis macularius) to fill the knowledge gap between traditional models of poikilothermic (zebrafish) and ...
Martina Gregorovicova   +5 more
wiley   +1 more source

Glycosylation of the murine cardiac channel TRPM4 is altered by the pathogenic p.I376T variant

open access: yesExperimental Physiology, EarlyView.
Abstract TRPM4 is a calcium‐activated, voltage‐modulated, non‐selective cation channel expressed in various tissues, including the heart. In 2016, we reported on a large French family with progressive heart block type I carrying the variant TRPM4 p.I376T.
Sabrina Guichard   +6 more
wiley   +1 more source

Reversible Chronotropic Incompetence in Early Cardiac Sarcoidosis Assessed by Serial Exercise Echocardiography. [PDF]

open access: yesJACC Case Rep
Katsui Y   +8 more
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Left Atrioventricular Coupling Index: A Comprehensive Review of the Literature. [PDF]

open access: yesLife (Basel)
Tsiamis N   +14 more
europepmc   +1 more source

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