Results 51 to 60 of about 88,913 (308)

Ionic basis of a differential effect of adenosine on refractoriness in rabbit AV nodal and atrial isolated myocytes [PDF]

, 1999
Methods: The whole cell patch clamp technique was used to record action potentials and ion currents in AV nodal and left atrial myocytes isolated enzymatically from rabbit hearts.
Kane, K.A., Rankin, A.C., Workman, A.J.
core   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Atrioventricular Reciprocating Tachycardia Mediated by Twin Atrioventricular Nodes

JACC: Clinical Electrophysiology, 2016
A 21-year-old man with univentricular and uniatrial heart came for a third attempt at ablation of recurrent supraventricular tachycardia. He had undergone a previous cardiac surgery of a Blalock–Taussig shunt, and bidirectional Glenn, and the electrophysiological study revealed an ...
Antonio, Frontera, Darren, Hooks, Bernard, Kreitmann, Jean-Benoit, Thambo, Michel, Haïssaguerre, Nicolas, Derval   +5 more
openaire   +2 more sources

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Making Mobile Leaflets: Biomechanical Forces in Atrioventricular Valve Formation

Cells
Atrioventricular valves prevent the backward flow of blood from the ventricles to the atria and are essential for the efficient pumping of blood throughout the body.
Anji Yang, Renee Wei-Yan Chow
doaj   +1 more source

Cesarean section under spinal anesthesia in acquired complete atrioventricular block without a pacemaker: A case report

Clinical Case Reports, 2019
Pregnancy with complete atrioventricular block is rare, and its perioperative management is controversial. We successfully managed cesarean section in a pregnancy with acquired complete atrioventricular block under spinal anesthesia without a pacemaker ...
Shungo Aratake, Atsushi Yasuda, Shigehito Sawamura   +2 more
doaj   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source

Bloqueio atrioventricular de 2° grau do tipo I Mobitz após aplicação de penicilina benzatina: relato de caso Bloqueo atrioventricular de 2º grado tipo Mobitz I después de la aplicación de penicilina benzatina: relato de caso Second degree atrioventricular block Mobitz type I after administration of benzathine penicillin: case report

Revista Brasileira de Anestesiologia, 2009
JUSTIFICATIVA E OBJETIVOS: O bloqueio atrioventricular de 2° grau do tipo I de Mobitz é observado como alteração transitória na presença de infarto de parede inferior ou de intoxicação medicamentosa.
Lúcia de Sousa Belém, Cristiano Aparecido Cavalcante Inácio   +1 more
doaj   +1 more source

Atrioventricular junctional tachycardias

, 2016
Atrioventricular junctional tachycardias comprise atrioventricular nodal reentrant tachycardia and non-reentrant junctional tachycardias, such as non-paroxysmal junctional tachycardia, focal junctional tachycardia, and non-reentrant atrioventricular ...
Bernard J. Gersh, Demosthenes G. Katritsis, A. John Camm   +2 more
core   +1 more source

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source