Results 211 to 220 of about 47,626 (295)

Trametinib Therapy for Hypertrophic Cardiomyopathy and Pulmonary Hypertension in a Child With RAF1‐Related Noonan Syndrome (p.Ser257Leu): A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case describes a female infant with RAF1‐related Noonan syndrome who developed severe hypertrophic obstructive cardiomyopathy, pulmonary hypertension, and cardiorespiratory failure that responded to trametinib treatment but ultimately progressed to death following dose tapering and discontinuation of therapy. To the best of our knowledge,
C. Noah Nilsson   +8 more
wiley   +1 more source

BRASH Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT BRASH syndrome is a life‐threatening clinical entity characterized by Bradycardia, Renal failure, Atrioventricular (AV) blockade, Shock, and Hyperkalemia. This syndrome is often triggered in patients on AV nodal blocking agents who develop acute kidney injury, leading to a “vicious cycle” of worsening bradycardia and renal dysfunction.
Sowdo Nur Iyow   +4 more
wiley   +1 more source

Successful Everolimus Therapy for Atrioventricular Block Due to Cardiac Rhabdomyoma Associated With Tuberous Sclerosis Complex. [PDF]

open access: yesJACC Case Rep
Baba S   +8 more
europepmc   +1 more source

A Case Report of PR Interval Prolongation Caused by Amlodipine

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Amlodipine is a widely used dihydropyridine calcium channel blocker. Its effects on the cardiac conduction system, especially PR interval prolongation, are rare but clinically important. We report a 25‐year‐old healthy male subject in a clinical trial with baseline first‐degree atrioventricular block (PR interval 230 ms).
Zhiying Fu   +3 more
wiley   +1 more source

Atrioventricular Blocks

open access: yes, 2019
Acosta Velez, Juan Gabriel   +4 more
  +6 more sources

Beta Blocker Toxicity at Therapeutic Doses: A Look Into Carvedilol Use in the Elderly

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Beta‐blocker toxicity does not occur only in overdose situations. In vulnerable populations such as children and the elderly, therapeutic doses may produce cumulative toxic effects similar to those seen in acute overdose. These patients require monitoring that extends beyond basic laboratory investigations to preempt cumulative toxicity.
Samuel Amo‐Tachie
wiley   +1 more source

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